Results 21 to 30 of about 138,045 (265)

Experimental substantiation of effectively administration of vinboron for analgesic activity increase of ibuprofen

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Background. The increase of NSAIDs safety is current direction of modern pharmacology, because of so-called "class-specific" adverse reactions, which are common to this class, and the leading place among them is occupied by gastro-intestinal toxicity. In
F. V. Hladkykh , N. H. Stepaniuk
doaj   +1 more source

CNS DEPRESSANT, ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CERTAIN OXANILAMIDE DERIVATIVES [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1983
The present study was designed to evaluate the CNS depressant, analgesic and antiinflammatory activity of six N- {D-threo(-)-1-(p-nitrophenyl)-1,3-dihydroxyisopropyl}-N-4-substituted carbamyol-3-hydroxyoxanilamides.
H. El-Bitar
doaj   +1 more source

Study of Analgesic activity of Bauhinia racemosa lam in Rats [PDF]

open access: yesVeterinary World, 2009
The present study was carried out to evaluate the analgesic activity of the stem bark of the Bauhinia racemosa plant in rats.weighing around 150-200g. Aqueous & alcoholic extracts of dried stem bark of Bauhinia racemosa Lam.
V.I.Borikar   +2 more
doaj  

New series of hydrazinyl thiazole derivatives of piperidin-4-one: Synthesis, structural elucidation, analgesic activity and comparative structure activity relationship

open access: yesPakistan Journal of Pharmaceutical Sciences, 2021
Seven new hydrazinyl thiazole derivatives of piperidin-4-one (PE3-PE9) have been synthesized by cyclization of intermediate thiosemicarbazone derivative (PE2).
Rubina Siddiqui   +5 more
doaj   +1 more source

Anticonvulsant and analgesic activities of crude extract and its fractions of the defensive secretion from the Mediterranean sponge, Spongia officinalis

open access: yesCancer Cell International, 2012
This study progresses in the direction of identifying component(s) from the Mediterranean sponge, Spongia officinalis with anticonvulsant and analgesic activities.
Dellai Afef   +4 more
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

The Analgesic and Anti-Inflammatory Activity of in Balb/c Mice

open access: yesJournal of Evidence-Based Complementary & Alternative Medicine, 2017
Linum usitatissimum L is traditionally used for relief of pain and inflammation. In this study, the analgesic and anti-inflammatory effects of this plant were evaluated. Xylene test was used for anti-inflammatory evaluation in which 48 mice were randomly
Mahmoud Rafieian-kopaei PhD   +3 more
doaj   +1 more source

Evaluation of analgesic, antioxidant and cytotoxic activities of ethanol extract of Clerodendrum viscosum Vent

open access: yesJournal of Applied Pharmaceutical Research, 2021
Clerodendrum viscosum Vent. is a very common plant in Bangladesh which is locally familiar as “Bhat” or “Ghetu”. Here, the ethanol extract of whole plant part of C.
Sujan Chandra Das   +3 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino   +25 more
wiley   +1 more source

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