Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates [PDF]
, 2016 Fentanyl is a powerful opiate analgesic typically used for the treatment of severe and chronic pain, but its prescription is strongly limited by the well-documented side-effects.
Benyhe, Sa ́ndor +18 more
core +1 more source
Microwave-assisted synthesis, characterization and biological activity of novel pyrazole derivatives
Journal of Saudi Chemical Society, 2014 A series of 1-(4-substitutedphenyl)-3-phenyl-1H-pyrazole-4-carbaldehydes 4a–l have been synthesized and tested for their biological activities. Formation of the pyrazole derivatives was achieved by treating with Vilsmeier-Haack reagent.
Theivendren Panneer Selvam +3 more
doaj +1 more source
Novel 6β-acylaminomorphinans with analgesic activity [PDF]
European Journal of Medicinal Chemistry, 2013 Aminomorphinans are a relatively young class of opioid drugs among which substances of high in vitro efficacy and favorable in vivo action are found. We report the synthesis and pharmacological evaluation of novel 6β-acylaminomorphinans. 6β-Morphinamine and 6β-codeinamine were stereoselectively synthesized by Mitsunobu reaction.
András, Váradi +8 more
openaire +3 more sources
7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects [PDF]
, 2019 Mitragynina speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction.
Ansonoff, Michael +12 more
core +3 more sources
Journal of Applied Pharmaceutical Research, 2021 Clerodendrum viscosum Vent. is a very common plant in Bangladesh which is locally familiar as “Bhat” or “Ghetu”. Here, the ethanol extract of whole plant part of C.
Sujan Chandra Das +3 more
doaj +1 more source
Investigation of Origanum compactum essential oil for analgesic and anti-inflammatory activities [PDF]
E3S Web of Conferences, 2021 Origanum compactum Benth. has been widely used in moroccan traditional medicine for various therapeutic treatments. Belonging to the same genus, O. onites was found to have marked analgesic and anti-inflammatory activities.
Hamamouchi Jamila +2 more
doaj +1 more source
Analgesic and Hepatoprotective Activity of Methanolic Leaf Extract of Ocimum gratissimum (L.). [PDF]
, 2012 The methanolic extract of Ocimum gratissimum (L.) leaves was screened for analgesic and hepatoprotective activity in albino rats, respectively. The use of the hot-plate method to study central analgesic activity of the leaves extract in albino rats ...
Akubugwo, E. I. +4 more
core +1 more source
Indian Journal of Pain, 2015 Background: Allopurinol and febuxostat are xanthine oxidase inhibitors which are used in the treatment of hyperuricemia and gout. Pain is one of the important symptoms in gout patients.
Promod D Shankpal +4 more
doaj +1 more source
EFFECT OF DIFFERENT DOSES OF PUMPKIN SEED OIL AS AN ANTI-INFLAMMATORY AND ANALGESIC ON MICE
The Iraqi Journal of Agricultural science, 2020 To evaluate the role of anti-inflammatory and analgesicof Iraqi pumpkin seed oil. The oil seed (25-100 mg / kg) were investigated using various experimental models for analgesic and anti-inflammatory benefit.
N. Z. yahya
doaj +1 more source
Sugar Palm Fruits (Arenga pinnata) as Potential Analgesics and Anti-Inflammatory Agent
MCBS (Molecular and Cellular Biomedical Sciences), 2019 Background: Sugar palm fruit (Arenga pinnata) is used for osteoarthritis empirically. It also has antioxidant activity and showed inhibition to lipoxygenase activity. The study about analgesic and anti-inflammatory activities of sugar palm fruit is still
Evi Sovia, Dian Anggraeny
doaj +1 more source