Results 61 to 70 of about 225,759 (311)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

A look inside the association codeine-paracetamol: clinical pharmacology supports analgesic efficacy [PDF]

, 2015
Acute and chronic pain often requires a multimodal approach. Combination therapy reduces the number of individual daily administrations and improves patient's compliance with the prescribed analgesic treatment. Despite the association codeine/paracetamol
COLUZZI, FLAMINIA, MATTIA, Consalvo
core  

Bioactivity-guided mass spectral net working reveals a new set of allbicidin derivatives from Xanthomonas albilineans [PDF]

, 2016
Albicidin is produced by the sugarcane pathogenic bacterium Xanthomonas albilineans and is a potent antibiotic specifically targeting the bacterial DNA gyrase with an IC50 value in the nanomolar range.
Cociancich, Stéphane, Dang, Tam, Dorrestein, Pieter C., Pesic, Alexander, Petras, Daniel, Royer, Monique, Süssmuth, Roderich   +6 more
core   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source

Evaluation of the analgesic and anti-inflammatory activity of fixed dose combination: Non-steroidal anti-inflammatory drugs in experimental animals

Indian Journal of Dental Research, 2014
Background: In India, a number of fixed dose drug combinations of non-steroidal anti-inflammatory drugs (NSAID′s) are available, often as over-the-counter products. These combinations are being prescribed too.
Amit Lahoti, Bhupinder S Kalra, Uma Tekur   +2 more
doaj   +1 more source

Psychosocial interventions for pain management in older adults with dementia: A systematic review of randomized controlled trials [PDF]

, 2019
Aim: To assess the effectiveness of psychosocial interventions on pain in older adults living with dementia. Design: A systematic review with meta-analysis of randomized controlled trials.
Jones, Cindy, Moyle, Wendy, Pu, Lihui, Todorovic, Michael   +3 more
core   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Pharmacological and Structure-Activity Relationship Evaluation of 4-aryl-1-Diphenylacetyl(thio)semicarbazides

Molecules, 2014
This article describes the synthesis of six 4-aryl-(thio)semicarbazides (series a and b) linked with diphenylacetyl moiety along with their pharmacological evaluation on the central nervous system in mice and computational studies, including ...
Monika Wujec, Ewa Kędzierska, Edyta Kuśmierz, Tomasz Plech, Andrzej Wróbel, Agata Paneth, Jolanta Orzelska, Sylwia Fidecka, Piotr Paneth   +8 more
doaj   +1 more source

An overview of anti-diabetic plants used in Gabon: Pharmacology and Toxicology [PDF]

, 2018
© 2017 Elsevier B.V. All rights reserved.Ethnopharmacological relevance: The management of diabetes mellitus management in African communities, especially in Gabon, is not well established as more than 60% of population rely on traditional treatments as ...
A. Souza, Abdelgadir, Abdu-Aguye, Abdulrazaq, Abubakar, Adebayo, Adedoyin, Adelusi, Ademuyiwa, Adeneye, Adeneye, Adeneye, Adeneye, Aderibigbe, Adeyemi, Adisa, Adler, Agbor, Agnaniet, Agunbiabe, Agyare, Ajaiyeoba, Ajaiyoeba, Ajao, Ajayi, Akah, Akash, Akinloye, Akpanyung, Aladodo, Alaribe, Amole, Anaduaka, Anosike, Anowi, Anowi, Antia, Anyanwu, Apers, Areola, Arthur, Asadu, Asha, Ashraf, Asolkar, Assob, Asuquo, Atangwho, Atawodi, Atawodi, Aw, Awah, Awe, Aziba, B. Bading Taika, Balasubramanian, Bamisaye, Bapna, Bardi, Bayan, Bella, Ben-Chioma, Bera, Biney, Bisong, Brantley, Calapai, Campbell, Campbell-Tofte, Capasso, Chika, Chokshi, Chris-Ozoko, Coolborn, Coria-Téllez, Da-Costa-Rocha, Dadzeasah, Dahake, Das, Dhanabalan, Djeussi, Djimeli, Djomeni, Djomeni Dzeufiet, Effiong, Effiong, Effo, Eidi, Ejike, El-Demerdash, Elufioye, Elumalai, Eluwa, Eneh, Erharuyi, Erhirhie, Eteng, Etuk, Ewenighi, Ewere, Eyong, Eze, Ezeasor, Ezejindu, Ezejiofor, Ezeokeke, Ezike, Ezuruike, Fang-Chui, Farzaei, Fernand, Ferreira, Feuya Tchouya, Feuya Tchouya, Fongang, Fred-Jaiyesimi, Gandhare, Ganesh, Gbadegesin, Gboeloh, Gemede, Ghani, Ghiware, Gomez-Flores, Gondi, Goutarel, Gupta, Gutierrez, H.P. Bourobou Bourobou, Halim, Hamzah, Hansen, Helfer, Hossain, Houghton, Houël, Huang, Huang, Husain, Husin, Ibibia, Igbe, Igboasoiyi, Ilodigwe, Ilodigwe, Ilusanya, Inya-Agha, Iroanya, Irondi, Irondi, Ishola, Iwu, Iyamah, Jawonisi, Juárez-Rojop, Juárez-Rojop, Kadima, Kaiser, Kamagate, Kamboj, Karimi, Karioti, Kathirvel, Kazeem, Kazeem, Kengni, Kengni, Khodabakhsh, Kolawole, Kouakou, Koudou, Kouitcheu Mabeku, Krishna, Kubilienė, Kuete, Kuete, Kuete, Kulkarni, Kumar, Kumar, Kumar, Kupchan, L. Lione, L.S. MacKenzie, Lakshmi, Lamidi, Lawal, Lawal, Laxane, Lee, Li, Lima, Ludvik, Ludvik, Luka, M. Bouckandou, Mabeku, Madingou, Madingou, Malviya, Manga, Maniyar, Manjur, Manvitha, Mathur, Maurya, Mačiulaitis, Mbiantcha, Mebale, Mengome, Midawa, Miranda-Osorio, Mishra, Miura, Mohamed, Mohammed, Mohammed, Mohammed, Mohammed, Momoh, Montasser, Muhammad, Muhammad, Muhammad, Muhammad, Muttaka, Nabukenya, Nakavuma, Naseri, Naskar, Navghare, Ndam, Nessa, Ngoc, Ngondi, Ngondi, Ngueguim, Ngueguim, Nishimura, Niyonzima, Nkono Ya Nkono, Nkono Ya Nkono, Ntyonga-Pono, Nwamarah, Nweze, Nwodo, Nwokocha, Nyunaï, Nyunaï, N’doua, N’guessan, N’Guessan, Obiang, Obiudu, Ocho-Anin Atchibri, Oduola, Oduola, Ofusori, Ogbonnia, Ogunrinola, Ojewole, Ojewole, Ojewunmi, Ojewunmi, Ojiako, Okeke, Okokon, Okokon, Okokon, Okolie, Okolo, Okonkwo, Olajide, Olaleye, Olatokunboh, Olivier, Olowu, Olubomehin, Ombra, Omodamiro, Omonkhua, Ong, Onyekwe, Osabede, Osadebe, Osigwe, Ouédraogo, Oyewusi j, Ozsoy-Sacan, Padilla-Camberos, Palaksha, Panda, Panda, Parle, Passoni, Patel, Patil, Ping, Pochapski, Pour, Pérez, Rajesh, Raji, Rauf, Ravi, Renjith, Rong, Rosemary, Roy, Sabitha, Sagnia, Santas, Satyaprakash, Saxena, Seung, Shah, Sharma, Sharma, Sharma, Shittu, Silva, Singh, Singh, Sio, Somova, Souza, Sowemimo, Sudhakar, Sule, Sunday, Sunday, Suryawanshi, Sutar, Swargiary, Swathi, Taj Eldin, Talreja, Tan Paul, Tanayen, Tchamadeau, Teugwa, Thongsom, Titanji, Tjeck, Togola, Toma, Toma, Trabelsi, Uchechi, Ufelle, Umoh, Vannamalar, Varghese, Varghese, Vashishtha, Verma, Verma, Vijayalakshmi, Vikram, Vliet, Wang, Wang, Wauthoz, Woode, Yakubu, Yasir, Yeap, Yessoufou, Yokozawa, Yousuf, Yu, Zakiah, Zhang, Zhao, Zheng   +374 more
core   +4 more sources

Airborne 1O2 Delivery via a Superhydrophobic Dressing as a Pathway to Next‐Generation Wound Therapies, an in Vivo Murine Burn Model Study

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the SH bandage placed on an infected burn wound and its role in wound healing. A superhydrophobic PDMS membrane coated with the PS verteporfin is placed over the wound area and illuminated with a red laser at 690 nm, generating airborne 1O2 above the tissue.
Fernanda Viana Cabral, QianFeng Xu, Natalie Eidenschink, Pareesha Haresh, Alessandra Nara de Souza Rastelli, Jeremy Goverman, Alexander Greer, Alan M. Lyons, Tayyaba Hasan   +8 more
wiley   +1 more source