Results 51 to 60 of about 225,759 (311)

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Perceived Impacts and Predictors of Cannabis Products used by Rheumatology Patients in Alberta: A Multivariable Analysis of Cross‐sectional Survey Data

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among rheumatology patients, and their associations with patient factors, patient reported perceived side effects and positive impacts. Methods An online survey (delivered from March to November 2022) was distributed by Alberta Health Services to ...
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Dose comparative evaluation of analgesic activity of simvastatin in wistar rats

National Journal of Physiology, Pharmacy and Pharmacology, 2019
Background: Pain is defined as an unpleasant sensation and emotional experience associated with or without tissue damage. Analgesics are the drugs that relieve pain. Statins are mainly employed in the treatment of hyperlipidaemias. Simvastatin belongs to
Krishnagouda Patil, Suneel Kumar Reddy
doaj   +1 more source

Depressive symptoms are associated with analgesic use in people with Alzheimer's disease: Kuopio ALSOVA study. [PDF]

, 2015
Neuropsychiatric symptoms of Alzheimer's disease (AD) such as depression may be associated with pain, which according to the literature may be inadequately recognized and managed in this population.
ALSOVA Study Group, ., Bell, JS, Gilmartin, JF, Hallikainen, I, Koivisto, AM, Lönnroos, E, Martikainen, J, Salo, L, Törmälehto, S, Väätäinen, S   +9 more
core   +2 more sources

Electroactive Metal–Organic Frameworks for Electrocatalysis

Advanced Functional Materials, EarlyView.
Electrocatalysis is crucial in sustainable energy conversion as it enables efficient chemical transformations. The review discusses how metal–organic frameworks can revolutionize this field by offering tailorable structures and active site tunability, enabling efficient and selective electrocatalytic processes.
Irena Senkovska, Yutong Luo, Ruyan Zhao, Jianjun Zhang, Mingchao Wang, Xinliang Feng, Eike Brunner, Stefan Kaskel   +7 more
wiley   +1 more source

The Analgesic and Anti-Inflammatory Activity of in Balb/c Mice

Journal of Evidence-Based Complementary & Alternative Medicine, 2017
Linum usitatissimum L is traditionally used for relief of pain and inflammation. In this study, the analgesic and anti-inflammatory effects of this plant were evaluated. Xylene test was used for anti-inflammatory evaluation in which 48 mice were randomly
Mahmoud Rafieian-kopaei PhD, Abdollah Shakiba MD, Mehrnoosh Sedighi PhD Cand., Mahmoud Bahmani PhD Cand.   +3 more
doaj   +1 more source

Metabotropic glutamate receptor 2/3 (mGluR2/3) activation suppresses TRPV1 sensitization in mouse, but not human sensory neurons [PDF]

, 2018
The use of human tissue to validate putative analgesic targets identified in rodents is a promising strategy for improving the historically poor translational record of preclinical pain research.
Baranger, David A.A., Gereau, Robert W, McIlvried, Lisa V, Pullen, Melanie Y, Sheahan, Tayler D, Valtcheva, Manouela V   +5 more
core   +2 more sources

Self‐Assembled Nanoclay Gel With Spheroid MSC‐Derived Exosome Mimetics to Integrate Demineralized Bone Matrix and Noggin‐Targeting miRNA for Synergistic Osteogenesis

Advanced Functional Materials, EarlyView.
We report a versatile nanoclay gel carrier platform that enhances the osteogenic efficacy of demineralized bone matrix (DBM) by integrating nanoclay‐based self‐assembly with cell‐derived exosome mimetics loaded with noggin‐targeting miR‐200c. This design amplifies BMP signaling, thereby promoting DBM‐mediated osteogenesis and offering a promising ...
Changlu Xu, Zhi Li, Minjee Kang, Ruoyu Sheng, Bing Han, Yiqing Chen, Tara Aghaloo, Min Lee   +7 more
wiley   +1 more source

Phytochemical Profiling and Bio-Potentiality of Genus Scutellaria: Biomedical Approach

Biomolecules, 2022
Scutellaria (Lamiaceae) comprises over 360 species. Based on its morphological structure of calyx, also known as Skullcap, it is herbaceous by habit and cosmopolitan by habitat. The species of Scutellaria are widely used in local communities as a natural
Muddaser Shah, Sidra Mubin, Syed Shams ul Hassan, Priti Tagde, Obaid Ullah, Md. Habibur Rahman, Ahmed Al-Harrasi, Najeeb Ur Rehman, Waheed Murad   +8 more
doaj   +1 more source

Antipyretic activity of azima tetracantha in experimental animals [PDF]

, 2011
In the present study, the ethanolic leaf extract of Azima tetracantha Lam (A. tetracantha) was investigated for antipyretic activity in rats using Brewer’s yeast induced Pyrexia. The leaves of A.
Tajuddin Nargis Begum, Mohamed Hussain Muhammad Ilyas, Arumugam Vijaya Anand , Int J Cur Biomed Phar Res.
core