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Cyclodextrin nanosponges are solid nanoparticles, designed by cross-linking of cyclodextrin polymer; it has been used widely as a good delivery system for water insoluble drugs.
Dalia A. Gaber +7 more
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Acute low back pain (LBP) stands as a leading cause of activity limitation and work absenteeism, and its associated healthcare expenditures are expected to become substantial when acute LBP develops into a chronic and even refractory condition. Therefore,
Magdi Hanna +2 more
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Association between WHO First-Step Analgesic Use and Risk of Breast Cancer in Women of Working Age
We assessed the association between breast cancer and analgesic use in women of a specific working-age group. The Korean National Health Insurance Service–National Sample Cohort database (KNHIS–NSC) data were analyzed.
Hyun Sook Oh, Hwa Jeong Seo
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Is PONV still a problem in pediatric surgery: a prospective study of what children tell us
BackgroundPostoperative nausea and vomiting (PONV) is an unpleasant complication after surgery that commonly co-occurs with pain. Considering the high prevalence among pediatric patients, it is important to explore the main risk factors leading to PONV ...
Brigitte Messerer +8 more
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Do NSAIDs and Other Pain Relief Drugs Can Inhibit the Growth of Lactobacillaceae?
Non-steroidal anti-inflammatory drugs (NSAIDs) commonly used in clinical practice may cause gastrointestinal injuries and influence the gut microbiota.
Kruszewska Hanna +2 more
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Due to the negative effects caused to the natural environment by the presence of pharmaceutical-type traces and other pollutants in wastewater, it is necessary to develop and optimize efficient treatment systems.
Eva Sandrith Baquero +2 more
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The objective: to evaluate the effect of combined use of analgesics, dalargin and tissue metabolism correctors on endocrine-metabolic disorders in patients with thoracoabdominal trauma who were injured in road accidents.Subjects and methods.
A. G. Miroshnichenko +9 more
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Effect of postoperative non-steroidal anti-inflammatory drugs on anastomotic leakage after pancreaticoduodenectomy [PDF]
Background Although the association between an increase in anastomotic leakage (AL) and non-steroidal anti-inflammatory drugs (NSAIDs) has been reported in gastrointestinal surgeries, this issue has rarely been addressed for pancreaticoduodenectomy (PD).
Susie Yoon +6 more
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Mechanisms and implications in gene polymorphism mediated diverse reponses to sedatives, analgesics and muscle relaxants [PDF]
Responses to sedatives, analgesics and muscle relaxants vary among patients under general anesthesia, which could be ascribed to the disparities of clinical characteristics and genetic factors of individuals.
Yan Sun +4 more
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Selective kappa-opioid receptor (KOR) agonists are considered a promising group of substances for developing opioid analgesics characterised with an original mechanism of action without the risk of respiratory depression and drug addiction.
O. V. Verle +5 more
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