Results 1 to 10 of about 392,664 (239)

Barriers and facilitators encountered by family physicians prescribing opioids for chronic non-cancer pain: a qualitative study

Health Promotion and Chronic Disease Prevention in Canada, 2021
IntroductionHarms caused by prescription opioid analgesics (POAs) have been identified as a major international public health concern. Recent statistics show rising numbers of opioid-related deaths across Canada.
Joshua Goodwin, Susan Kirkland
doaj   +1 more source

Risk of Hospital-Acquired Acute Kidney Injury among Adult Opioid Analgesic Users: A Multicenter Real-World Data Analysis

Kidney Diseases, 2023
Introduction: Comprehensive data on the risk of hospital-acquired (HA) acute kidney injury (AKI) among adult users of opioid analgesics are lacking.
Mingjing Pi, Sheng Nie, Licong Su, Yanqin Li, Yue Cao, Peiyan Gao, Yuxin Lin, yan zha, Yongjun Shi, Hua Li, Jiajun Zhao, Yaozhong Kong, Guisen Li, Ying Hu, Huafeng Liu, Qijun Wan, Chunbo Chen, Bicheng Liu, Qiongqiong Yang, Guobin Su, Yilun Zhou, Jianping Weng, Gang Xu, Hong Xu, Ying Tang, Mengchun Gong, Fan Fan Hou, Xin Xu   +27 more
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Adverse selection? A multi-dimensional profile of people dispensed opioid analgesics for persistent non-cancer pain. [PDF]

PLoS ONE, 2013
OBJECTIVES: This study investigates utilisation patterns for prescription opioid analgesics in the Australian community and how these are associated with a framework of individual-level factors related to healthcare use.
Kris D Rogers, Anna Kemp, Andrew J McLachlan, Fiona Blyth   +3 more
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IUPHAR Review - Bivalent and bifunctional opioid receptor ligands as novel analgesics

Pharmacological Research, 2023
Though efficacious in managing chronic, severe pain, opioid analgesics are accompanied by significant adverse effects including constipation, tolerance, dependence, and respiratory depression.
Kyle J. Rehrauer, Christopher W. Cunningham   +1 more
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In Silico Simulation of the Systemic Drug Exposure Following the Topical Application of Opioid Analgesics in Patients with Cutaneous Lesions

Pharmaceutics, 2021
The use of opioid analgesics in treating severe pain is frequently associated with putative adverse effects in humans. Topical agents that are shown to have high efficacy with a favorable safety profile in clinical settings are great alternatives for ...
Maksim Khotimchenko, Victor Antontsev, Kaushik Chakravarty, Hypatia Hou, Jyotika Varshney   +4 more
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Too much or too little opioids to patients receiving opioid agonist therapy in Norway (2013–2017): a prospective cohort study

BMC Health Services Research, 2020
Background Dispensations of opioid analgesics to patients on opioid agonist therapy (OAT) may increase the risk of overdoses. The current study’s objectives are to investigate the dispensation rates and mean daily doses of dispensed opioid analgesics ...
Jørn Henrik Vold, Svetlana Skurtveit, Christer Aas, Kjell Arne Johansson, Lars Thore Fadnes   +4 more
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Temporal trend of opioid and nonopioid pain medications: results from a national in-home survey, 2001 to 2018

PAIN Reports, 2022
. Introduction:. The opioid epidemic persists in the United States. The use of opioid medications is often assessed by claims data but potentially underestimated. Objectives:.
Yun Wang, Dan Wu, Alexandre Chan, Chih-Hung Chang, Vivian W.Y. Lee, Michael B. Nichol   +5 more
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Orofacial pain in oncology: use of a new analgesic peptide tafalgin

Опухоли головы и шеи, 2023
In patients with head and neck tumors severe pain is more common than in patients with malignant neoplasms of other locations. At a third of patients, pain is the first characteristic of the disease, and after diagnosis, one half of the patients are ...
G. R. Abuzarova, R. R. Sarmanaeva, G. S. Alekseeva, S. V. Kuznetsov, A. R. Gevorkov, N. A. Fedorenko, D. A. Zaretskaya   +6 more
doaj   +1 more source

Central nervous system (CNS) medications and polypharmacy in later life: cross-sectional analysis of the English Longitudinal Study of Ageing (ELSA)

BMJ Open, 2020
Objectives Many central nervous system (CNS) medications are considered potentially inappropriate for prescribing in older people; however, these medications are common in polypharmacy (≥5 medicines) regimens.
Natasha Slater, Simon White, Martin Frisher   +2 more
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Subtypes in Patients Taking Prescribed Opioid Analgesics and Their Characteristics: A Latent Class Analysis

Frontiers in Psychiatry, 2022
BackgroundOwing to their pharmacological properties the use of opioid analgesics carries a risk of abuse and dependence, which are associated with a wide range of personal, social, and medical problems.
Christian Rauschert, Nicki-Nils Seitz, Sally Olderbak, Sally Olderbak, Oliver Pogarell, Tobias Dreischulte, Ludwig Kraus, Ludwig Kraus, Ludwig Kraus   +8 more
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