Alimentary Pharmacology &Therapeutics, EarlyView.Prevalence of opioid use among adults with CD is high 2 years before and remains high 5 years after the 1st CD diagnosis. The use of opioids among adults with CD and reference individuals in Sweden has declined 2008–2021. ABSTRACT Background and Aims Population‐based data on prescribed opioid use among adults with Crohn's disease (CD) remain limited ...
Mehdi Osooli +17 more
wiley +1 more source
Comparative Efficacy of Dexmedetomidine and Remifentanil in Reducing Postoperative Pain and Opioid Use: A Systematic Review. [PDF]
CureusAl-Hassan A +4 more
europepmc +1 more source
Prognostic factors in bushfire‐affected koalas–Kangaroo Island bushfire response 2020
Australian Veterinary Journal, EarlyView.This study presents a retrospective analysis of clinical records data from koalas presenting for treatment following the large‐scale bushfire event on Kangaroo Island 2019–2020. The aim of the study was to identify prognostic factors for koalas affected by bushfire. Koalas (n = 199) were grouped based on their burn status in combination with their burn
O Funnell +6 more
wiley +1 more source
Additive effect of a single intravenous dose of acetaminophen administered at the end of laparoscopic hysterectomy on postoperative pain control with nefopam and fentanyl-based patient-controlled analgesia: a double-blind, randomized controlled trial. [PDF]
BMC AnesthesiolNam S, Yoo S, Park SK, Kim JT.
europepmc +1 more source
British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 1132-1156, April 2025.Abstract Structured medication reviews (SMRs) were introduced into the National Health Service (NHS) Primary Care to support the delivery of the NHS Long‐Term Plan for medicines optimization. SMRs improve the quality of care, reduce harm and offer value for money. However, evidence to support SMRs for patients with chronic kidney disease (CKD) stage G4‐
Cathy Margaret Pogson +3 more
wiley +1 more source
Sex-Related Analgesic Effects of Opioid-Based Anesthesia and Low-Opioid Anesthesia with Non-Opioid Postoperative Analgesia-A Clinical Observational Study. [PDF]
J Clin MedKosciuczuk U +4 more
europepmc +1 more source
Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial
BJU International, Volume 135, Issue 4, Page 638-647, April 2025.Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui +2 more
wiley +1 more source
Enhanced Recovery After Surgery (ERAS) Protocols in Orthopaedic Surgery: Opioids or Not Opioids? [PDF]
J Pain ResGrossi P.
europepmc +1 more source
BJU International, Volume 135, Issue 6, Page 977-986, June 2025.Objectives To assess the feasibility of trial recruitment and confirm that retroperitoneal robotic partial nephrectomy (RRPN) has the same oncological efficacy as transperitoneal robotic partial nephrectomy (TRPN), with time advantages and less peri‐operative morbidity, in a randomised controlled trial (RCT). Patients and Methods The study was designed
Sebastian Kälble +12 more
wiley +1 more source
ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system
British Journal of Pharmacology, EarlyView.G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison +15 more
wiley +1 more source