Results 191 to 200 of about 86,963 (292)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Opioid-Free Anesthesia Versus Opioid-Based Anesthesia in Pediatric Dental Day-Case Surgery: A Retrospective Cohort Study of Safety and Efficacy. [PDF]

Cureus
Khalaf AA, Nabil A, Ibrahim H, Bodhey M, Ahmed ZK.   +4 more
europepmc   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Analgesic effect of intravenous nefopam for postoperative pain in spine surgery: a meta-analysis of RCTs. [PDF]

Int J Physiol Pathophysiol Pharmacol
Pashazadeh MP, Nahavandi Z, Ghorbani A, Shakeri S, Abbasi M, Haghshoar S, Sayedsalehi S, Salimi O, Hafezi V, Khakpour Y, Farrokhi Z, Naziri M, Alizadeh H, Deravi N.   +13 more
europepmc   +1 more source

Knowledge, Attitude and Practice in Anxiety, Pain and Medical Emergency Management: A National Survey on 232 Italian Dental Students

European Journal of Dental Education, EarlyView.
ABSTRACT Background Anxiety, pain and medical emergencies are crucial concepts in the dental field. Dental students need training, but little is known of their competence on these topics. Aim The aim of this study was to assess the current state of Italian dental students' preparation for, attitudes to, and perceptions of medical emergency, anxiety and
Niccolò Giuseppe Armogida, Luigi Esposito, Gianrico Spagnuolo, Mariangela Cernera, Carlo Rengo, Luca Signorini, Antonino Fiorino   +6 more
wiley   +1 more source

Executive summary of the guideline for prescribing opioid analgesics for chronic non-cancer pain (third edition) by the Japan Society of Pain Clinicians. [PDF]

J Anesth
Kanai A, Iseki M, Iida H, Yamaguchi S, Oiwa A, Yonekura H, Iwashita N, Ueno H, Kimura Y, Takasusuki T, Yamaguchi K, Iida S, Ikemiya H, Oya R, Sugiyama Y, Tanabe K, Taniguchi A, Hattammaru Y, Mizogami M, Yamaguchi S, Yamada K, Fukui S.   +21 more
europepmc   +1 more source

Alpha‐2‐adrenoreceptor agonists as analgesic drugs in equine medicine

Equine Veterinary Education, EarlyView.
Summary Managing pain in horses is challenging despite the availability of nonsteroidal anti‐inflammatory drugs, local anaesthetics, opioids and α2‐adrenoreceptor agonists. While α2‐agonists are widely used for sedation and restraint, their analgesic properties remain underutilised.
J. A. E. Hubbell, J. Brandly, W. W. Muir III, J. Page, K. Hopster   +4 more
wiley   +1 more source

Trends in the use of opioid and non-opioid analgesics after TBI with and without polytrauma. [PDF]

Trauma Surg Acute Care Open
Medvecz AJ, Maiga AW, Dusetzina S, Guillamondegui OD, Wiese AD.   +4 more
europepmc   +1 more source

Aetiological relevance of haematological, biochemical and endocrine parameters on equine odontoclastic tooth resorption and hypercementosis (EOTRH)

Equine Veterinary Journal, EarlyView.
Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow, Anna M. Hain, Astrid Bienert‐Zeit   +2 more
wiley   +1 more source

Benefits of enhanced recovery after surgery in robotic nephrectomy. [PDF]

World J Urol
Schrock WP, Farrow JM, Backfish-White KM, Lima AM, Strup SE, Li J, Sundaram C, McCutchan AL.   +7 more
europepmc   +1 more source