Results 231 to 240 of about 62,305 (293)

Tapentadol-induced urticarial rash in a patient with acute pancreatitis.

Indian J Pharmacol
Deshidi S, Hanumanthu V, Mahajan G, Appasani S.   +3 more
europepmc   +1 more source

Opioid-based versus opioid-sparing patient-controlled analgesia using ketorolac and nefopam after total knee arthroplasty: a randomized, double-blind, non-inferiority trial. [PDF]

Korean J Anesthesiol
Han J, Jung H, Kim MK, Park YB, Min S.
europepmc   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Opioid consumption, availability, and policy alignment in primary hospice and palliative care in China: a multicomponent comparative analysis. [PDF]

Support Care Cancer
Fan Y, Ye Z, Jiang M, Jing L, Zhang H, Tang Z, Qiao H, Wang X, Zhang X, Tang Y, Liu L.   +10 more
europepmc   +1 more source

Cannabinoid CB1 allosteric ligands suppress inflammatory pain in male mice without tolerance, motor impairment, memory deficits or respiratory depression

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Positive allosteric modulators (PAMs) engage sites distinct from the orthosteric CB1 cannabinoid receptor binding site. GAT211, a racemic ligand, contains GAT228 (R) and GAT229 (S) enantiomers. Whether enantiomer‐mediated differences in allosteric activation or positive allosteric modulation translate into differences in
Ifeoluwa D. Solomon, Sumanta Garai, Ganesh A. Thakur, Andrea G. Hohmann   +3 more
wiley   +1 more source

Associations of Cannabis and Tobacco Use With Suicide Attempt, Suicide Death, and Overdose Death Among Veterans Prescribed Opioid Analgesics. [PDF]

Am J Prev Med
Nguyen N, Leonard S, Byers AL, Austin PC, Krebs EE, Sandbrink F, Bravata DM, Keyhani S.   +7 more
europepmc   +1 more source

Comparative analysis of analgesic mechanisms in craniotomy pediatric patients: a scoping review. [PDF]

Childs Nerv Syst
Jenkins A, Witten G, Azam F, Guirguis M, Shukla I, Patel S, Guirguis F, Farid M, O'Leary S, Barrie U, Aoun SG, Braga BP.   +11 more
europepmc   +1 more source

Withdrawal Syndrome Following Opioid Rotation: Tramadol and Its Unique Pharmacology. [PDF]

Cureus
Murphy MA.
europepmc   +1 more source

Effects and costs of a group-based educational intervention to reduce opioid use in people with chronic pain: I-WOTCH RCT.

Health Technol Assess
Sandhu HK, Booth K, Manchira Krishnan S, Abraham C, Alleyne S, Balasubramanian S, Betteley L, Bromilow T, Carnes D, Furlan AD, Gc VS, Haywood KL, Hill M, Iglesias-Urrutia CP, Lall R, Manca A, Mistry D, Moss JW, Newton S, Nichols VP, Noyes J, Padfield E, Rahman A, Seers K, Shaw J, Tang NK, Taylor SJ, Tysall C, Underwood M, Eldabe S.   +29 more
europepmc   +1 more source

Patient-controlled analgesia in transition: opioid-sparing strategies and the emergence of mechanism-based alternatives. [PDF]

Korean J Anesthesiol
Jeong JS.
europepmc   +1 more source