Cluster Analysis of Opioid Accessibility in the Carolinas Using Data from the ARCOS Database and an Enhanced Two-Step Floating Catchment Area Method [PDF]
, 2020 This study takes advantage of transaction level data from the U.S. Drug Enforcement Administration\u27s (DEA) Automation of Reports and Consolidated Orders System (ARCOS) database made newly available under court order by The Washington Post in July 2019.
Bunker, Michael T.
core +1 more source
Administration of Tramadol or Buprenorphine via the drinking water for post-operative analgesia in a mouse-osteotomy model [PDF]
, 2019 Adequate analgesia is essential whenever pain might occur in animal experiments. Unfortunately, the selection of suitable analgesics for mice in bone-linked models is limited. Here, we evaluated two analgesics - Tramadol [0.1 mg/ml (Tlow) vs.
Buttgereit, Frank +7 more
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PAIN Reports, 2018 . Introduction:. Cognitive performance and inflammation are altered in people with chronic low back pain (CLBP). Yet, the magnitude of these changes has been unclear because of the potential influence of opioid analgesics. Objectives:.
Georgia C. Richards +6 more
doaj +1 more source
Opioid Sparing Analgesics in Spine Surgery
Advances in Orthopedics, 2022 Combinations of various nonopioid analgesics have been used to decrease pain and opioid consumption postoperatively allowing for faster recovery, improved patient satisfaction, and decreased morbidity.
Logan A. Reed +3 more
doaj +1 more source
A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new $β$-arrestin inhibitor [PDF]
Pharmacological Research, 2025, 107597$\beta$-arrestins play pivotal roles in seven transmembrane receptor (7TMR) signalling and trafficking. To study their functional role in the regulation of specific receptor systems, current research relies mainly on genetic tools, as few pharmacological options are available.
arxiv +1 more source
Optimizing Return and Secure Disposal of Prescription Opioids to Reduce the Diversion to Secondary Users and Black Market [PDF]
arXiv, 2022 Opioid Use Disorder (OUD) has reached an epidemic level in the US. Diversion of unused prescription opioids to secondary users and black market significantly contributes to the abuse and misuse of these highly addictive drugs, leading to the increased risk of OUD and accidental opioid overdose within communities.
arxiv
Tapentadol extended release for the management of chronic neck pain [PDF]
, 2017 BACKGROUND: The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER).
Coluzzi, Flaminia
core +1 more source
Molecules, 2020 Achieving effective pain management is one of the major challenges associated with modern day medicine. Opioids, such as morphine, have been the reference treatment for moderate to severe acute pain not excluding chronic pain modalities.
Abdelfattah Faouzi +2 more
doaj +1 more source
A novel behavioral fish model of nociception for testing analgesics [PDF]
, 2011 Pain is a major symptom in many medical conditions, and often interferes significantly with a person's quality of life. Although a priority topic in medical research for many years, there are still few analgesic drugs approved for clinical use.
Ana D. Correia +41 more
core +3 more sources
Clinical Observation of Olanzapine in Treatment of Nausea and Vomiting Caused by Opioid Analgesics
Zhongliu Fangzhi Yanjiu, 2018 Objective To observe the efficacy and side effects of olanzapine in the treatment of nausea and vomiting caused by opioid analgesics in cancer patients.
LI Daojun +3 more
doaj +1 more source