Results 11 to 20 of about 435,526 (355)
Electroencephalography and analgesics [PDF]
British Journal of Clinical Pharmacology, 2014 To assess centrally mediated analgesic mechanisms in clinical trials with pain patients, objective standardized methods such as electroencephalography (EEG) has many advantages.
Lasse P. Malver +5 more
semanticscholar +4 more sources
BMJ, The, 2015 Objective To study the association between benzodiazepine prescribing patterns including dose, type, and dosing schedule and the risk of death from drug overdose among US veterans receiving opioid analgesics. Design Case-cohort study.
Tae Woo Park +2 more
exaly +2 more sources
The unsolved case of “bone-impairing analgesics”. The endocrine effects of opioids on bone metabolism [PDF]
Therapeutics and Clinical Risk Management, 2015 The current literature describes the possible risks for bone fracture in chronic analgesics users. There are three main hypotheses that could explain the increased risk of fracture associated with central analgesics, such as opioids: 1) the increased ...
COLUZZI, FLAMINIA +3 more
core +4 more sources
Structure-based discovery of opioid analgesics with reduced side effects
Nature, 2016 Aashish Manglik +2 more
exaly +2 more sources
JAMA Network Open, 2021 Key Points Question How has prescribing of opioid analgesics and buprenorphine for opioid use disorder changed throughout the COVID-19 pandemic? Findings This cross-sectional study analyzed prescriptions from 90 420 353 patients and found that from March
J. Currie +3 more
semanticscholar +1 more source
Pain and Therapy, 2023 Acute low back pain (LBP) stands as a leading cause of activity limitation and work absenteeism, and its associated healthcare expenditures are expected to become substantial when acute LBP develops into a chronic and even refractory condition. Therefore,
Magdi Hanna +2 more
doaj +1 more source
Effect of postoperative non-steroidal anti-inflammatory drugs on anastomotic leakage after pancreaticoduodenectomy [PDF]
Korean Journal of Anesthesiology, 2022 Background Although the association between an increase in anastomotic leakage (AL) and non-steroidal anti-inflammatory drugs (NSAIDs) has been reported in gastrointestinal surgeries, this issue has rarely been addressed for pancreaticoduodenectomy (PD).
Susie Yoon +6 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Background: Given the limitations of three-step analgesic therapy and the extensive use of traditional Chinese medicine injections (TCMIs) for cancer-related pain (CRP), this network meta-analysis (NMA) aims to compare the efficacy and safety of ...
Pengli Su +5 more
doaj +1 more source
Animal Models and Experimental Medicine, 2021 Background Extended‐release buprenorphine (XR) is indicated for pain management in rodents, but little is known about its use in mice. This study aimed to investigate whether high dose XR effectively attenuates post‐operative hypersensitivity better than
Kaela Navarro +3 more
doaj +1 more source