Results 21 to 30 of about 449,058 (420)
Dexmedetomidine decreases stress post-operative in pediatrics
Egyptian Journal of Anaesthesia, 2022 Introduction Tracheal extubation causes hypertension and tachycardia. These associated hemodynamic changes are due to sympathetic discharge due to epipharyngeal and laryngeal stimulation.(1)Aim of work Dexmedetomidine is an effective sedative and ...
Taha Magdy AllamFarrag +3 more
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Metabolically Stable Neurotensin Analogs Exert Potent and Long-Acting Analgesia Without Hypothermia [PDF]
Behavioural Brain Research, 405:113189 (2021), 2021 The endogenous tridecapeptide neurotensin (NT) has emerged as an important inhibitory modulator of pain transmission, exerting its analgesic action through the activation of the G protein-coupled receptors, NTS1 and NTS2. Whereas both NT receptors mediate the analgesic effects of NT, NTS1 activation also produces hypotension and hypothermia, which may ...
arxiv +1 more source
Journal of Education and Health Promotion, 2020 CONTEXT: Inappropriate self-medication can increase chances of adverse drug reactions, disease aggravation, or drug interactions. Analgesics are most commonly used as self-medication. AIMS: The aim of this study was to evaluate and compare analgesic self-
Chaitali Ashish Chindhalore +2 more
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Analgesic Alkaloids Derived From Traditional Chinese Medicine in Pain Management
Frontiers in Pharmacology, 2022 Chronic pain is one of the most prevalent health problems. The establishment of chronic pain is complex. Current medication for chronic pain mainly dependent on anticonvulsants, tricyclic antidepressants and opioidergic drugs.
Wei Jiang +13 more
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Frontiers in Digital Health, 2022 Digital therapeutics (DTx, mobile medical apps, software as a medical device) are rapidly emerging as clinically effective treatments for diverse chronic diseases. For example, the Food and Drug Administration (FDA) has recently authorized a prescription
Hayam Y. Giravi +3 more
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Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog [PDF]
Eur J Pharmacol, 173174 (2020), 2020 Neurotensin (NT) exerts naloxone-insensitive antinociceptive action through its binding to both NTS1 and NTS2 receptors and NT analogs provide stronger pain relief than morphine on a molecular basis. Here, we examined the analgesic/adverse effect profile of a new NT(8-13) derivative denoted JMV2009, in which the Pro10 residue was substituted by a ...
arxiv +1 more source
Local infiltration with cocktail analgesics during 2 level lumbar spinal fusion surgery
Medicine, 2019 Background: Despite introducing novel analgesics, pain management for spine surgery remains a challenge. Multimodal pain control has recently gained popularity in surgical spine care.
Z. Ren +8 more
semanticscholar +1 more source
An overview of analgesics: NSAIDs, paracetamol, and topical analgesics
South African Family Practice, 2019 Pain is a complex and unique experience. It encompasses several pathways, involving nociceptive signal generation (transduction) and propagation (transmission), as well as perception and modulation of the nociceptive stimuli.
R. Van Rensburg, H. Reuter
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Dexmedetomidine: present and future directions [PDF]
Korean Journal of Anesthesiology, 2019 Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties.
Seongheon Lee
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The use of transdermal fentanyl in the treatment of cancer pain [PDF]
Archive of Oncology, 2002 The management of pain is complex having to take into consideration patient specific characteristics. Drug therapy should be individualized and managed based on numerous factors.
Radovanović Dragana +3 more
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