Results 21 to 30 of about 153,649 (263)

Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post‐operative hypersensitivity in an incisional pain model in mice (Mus musculus)

open access: yesAnimal Models and Experimental Medicine, 2021
Background Extended‐release buprenorphine (XR) is indicated for pain management in rodents, but little is known about its use in mice. This study aimed to investigate whether high dose XR effectively attenuates post‐operative hypersensitivity better than
Kaela Navarro   +3 more
doaj   +1 more source

The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods [PDF]

open access: yes, 1964
1. The forms of irritation causing inflammation and pain are reviewed, with reference to the significance of histamine, serotonin and bradykinin and in particular to the interrelationship between inflammation and pain. 2.
Wilhelmi, G.
core   +1 more source

Addressing the Global Tragedy of Needless Pain: Rethinking the United Nations Single Convention on Narcotic Drugs [PDF]

open access: yes, 2007
The lack of medical availability of effective pain medication is an enduring and expanding global health calamity. Despite important medical advances, pain remains severely under-treated worldwide, particularly in developing countries.
Allyn L. Taylor   +11 more
core   +2 more sources

Early morphological changes in the knee joint of rats after opioid exposure

open access: yesPatologìâ, 2019
The objective is to study early morphological changes of rats’ knee joint after experimental opioid exposure. Materials and methods. Research material is mature, non-breeding male rats 4.5 months old (n = 16) with body weight 80 g.
K. I. Voitsenko
doaj   +1 more source

Parameters of vibration stimulation for the relief of pain of different origins and locations [PDF]

open access: yesRehabilitacja Medyczna, 2018
The use of vibration stimulation in alleviating pain is an issue appearing more and more often in modern rehabilitation. The aim of the work was to review literature regarding the therapeutic usage of vibrations in analgesic activity. Searches based on
Alicja Pasterczyk-Szczurek   +2 more
doaj   +1 more source

The pain of low status: the relationship between subjective socio-economic status and analgesic prescriptions in a Scottish community sample [PDF]

open access: yes, 2016
There is a strong positive relationship between objective measures of socioeconomic status (OSS) and general health. However, there is an increasing interest in the relationship between health and subjective socioeconomic status (SSS), which describes ...
Fabio Sani   +10 more
core   +3 more sources

Analgesics for Dental Implants: A Systematic Review

open access: yesFrontiers in Pharmacology, 2021
Postsurgical pain is commonly associated with dental and oral surgery, and the use of analgesics has been investigated in the management of postoperative pain.
Matteo Melini   +4 more
doaj   +1 more source

The unsolved case of “bone-impairing analgesics”. The endocrine effects of opioids on bone metabolism [PDF]

open access: yes, 2015
The current literature describes the possible risks for bone fracture in chronic analgesics users. There are three main hypotheses that could explain the increased risk of fracture associated with central analgesics, such as opioids: 1) the increased ...
COLUZZI, FLAMINIA   +3 more
core   +3 more sources

Synthetic route towards potential bivalent ligands possessing opioid and D2/D3 pharmacophores [PDF]

open access: yesJournal of the Serbian Chemical Society, 2019
A scalable, cost-efficient and simple synthetic pathway towards potential bivalent opioid/dopamine receptor ligands was developed and optimized. Three novel compounds that contain both opioid and dopamine pharmacophores linked by the four methylene group
Jevtić Ivana I.   +3 more
doaj   +1 more source

Safety of opioid patch initiation in Australian residential aged care [PDF]

open access: yes, 2015
Explores opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Abstract Objective: To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Design:
Elizabeth Roughead   +2 more
core   +1 more source

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