Results 51 to 60 of about 271,989 (296)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Metaphors and Analogies in Pain Management – A Survey of 142 Healthcare Professionals

Indian Journal of Pain
Background: Metaphors and analogies are a good way of explaining medical concepts to our patients to help them understand their condition and treatment strategies. Objectives: To find out the opinions of healthcare professionals (HCPs) who manage chronic
Sanjeeva Gupta, Risha Gupta, Manohar Sharma, Prit Anand Singh   +3 more
doaj   +1 more source

Analogies between self-duality and stealth matter source [PDF]

, 2006
We consider the problem of a self-interacting scalar field nonminimally coupled to the three-dimensional BTZ metric such that its energy-momentum tensor evaluated on the BTZ metric vanishes.
Bogomolny E B, Bogomolny E B, Dunne G V, Dunne G V, Hassaine M, Jackiw R, Jackiw R, Mokhtar Hassaïne   +7 more
core   +2 more sources

Analogical Proportions and Analogical Reasoning - An Introduction [PDF]

, 2017
Analogical proportions are statements of the form “a is to b as c is to d”. For more than a decade now, their formalization and use have raised the interest of a number of researchers. In this talk we shall primarily focus on their modeling in logical settings, both in the Boolean and in the multiple-valued cases.
Prade, Henri, Richard, Gilles
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Labourer la terre, tisser la vie. Éclats d’analogies dans les Andes sud-péruviennes

Journal de la Société des Américanistes, 2012
Plough the earth, weave the life. Sparkles of analogies in the South Peruvian Andes. The ethnographic datum analyzed in this paper concerns the cultivation of an irrigated plot in a peasant community of the South Peruvian Andes (Calca, Cusco).
Ingrid Hall
doaj   +1 more source

Metaphor Types as Strategies for Teaching Regression to Novice Learners

Journal of Statistics and Data Science Education, 2022
Metaphors are well-known tools for teaching statistics to novices. However, educators might overlook metaphor theoretical developments that offer nuanced and testable perspectives on their pedagogical applications.
Dennis Tay
doaj   +1 more source

Exact solutions and physical analogies for unidirectional flows

, 2016
Unidirectional flow is the simplest phenomenon of fluid mechanics. Its mathematical description, the Dirichlet problem for Poisson's equation in two dimensions with constant forcing, arises in many physical contexts, such as the torsion of elastic beams,
Bazant, Martin Z.
core   +1 more source