Results 41 to 50 of about 222,112 (304)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Analogies in the historical development of IHL (1864–2001)

open access: yesInternational Review of the Red Cross
Analogies appear to permeate the entire domain of international humanitarian law (IHL), but as an independent subject of inquiry, they remain largely overlooked within IHL scholarship.
Pauline Lesaffre
doaj   +1 more source

Uso espontâneo de analogias por professores de biologia e o uso sistematizado de analogias: que relação? The spontaneous use of analogies by biology teachers and the use of systemic analogies: which works?

open access: yesCiência & Educação, 2003
Vários autores têm refletido sobre o papel das metáforas e das analogias tanto na produção do conhecimento em áreas específicas do saber, quanto na construção do conhecimento no âmbito do desenvolvimento de uma disciplina escolar.
Daniela Frigo Ferraz   +1 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Analogias produzidas por alunos do ensino médio em aulas de física

open access: yesRevista Brasileira de Ensino de Física
Analogias são consideradas recursos didáticos potencialmente úteis, pois servem para mediar o processo de aprendizagem de conceitos/fenômenos/assuntos desconhecidos, mediante o estabelecimento de relações de semelhança e diferença com situações ...
Luciana Bagolin Zambon   +1 more
doaj   +1 more source

Using Visual Analogies To Teach Introductory Statistical Concepts

open access: yesNumeracy, 2017
Introductory statistical concepts are some of the most challenging to convey in quantitative literacy courses. Analogies supplemented by visual illustrations can be highly effective teaching tools.
Jessica S. Ancker, Melissa D. Begg
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Circuit Theory Analysis of Acoustically Coupled Rooms

open access: yesRevista Elektrón, 2019
A circuit theory approach is presented for the analysis of acoustically coupled spaces. It is based on energy flow and balance with a similar analogy to the one used for solving dynamic thermal systems, where acoustic power is analog  to electric current
Federico Miyara
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Analogies in biology textbooks in zoology teaching [PDF]

open access: yesInvestigações em Ensino de Ciências, 2011
The biologic structures of living creatures are of difficult understanding for students, because they are usually unknown by those, in needs of strategic didactics in order to facilitate the student understanding. There are several strategies and methods
Saulo Cézar Seiffert Santos   +2 more
doaj  

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