Results 41 to 50 of about 26,307 (265)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Impact of Analogies and Metaphors in Propagating Misconceptions in Chemical Education

open access: yesShodh Sari
Analogies and metaphors have been used as teaching tools in chemical education to make complex concepts easier to understand. While they help students grasp ideas at first, these language and visual aids can also create lasting misconceptions that make ...
Dr Sandeep Kumar
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

AS CONCEPÇÕES DE NATUREZA NOS LIVROS DIDÁTICOS DE CIÊNCIAS

open access: yesEnsaio Pesquisa em Educação em Ciências
Análise das concepções de natureza dos livros didáticos sob uma perspectiva holística e transformadora. Fomenta discussões entre os profissionais da educação sobre o papel do livro como reprodutor das ideologias dominantes em relação aos recursos ...
Eliecília de Fátima Martins   +1 more
doaj   +1 more source

Labourer la terre, tisser la vie. Éclats d’analogies dans les Andes sud-péruviennes

open access: yesJournal de la Société des Américanistes, 2012
Plough the earth, weave the life. Sparkles of analogies in the South Peruvian Andes. The ethnographic datum analyzed in this paper concerns the cultivation of an irrigated plot in a peasant community of the South Peruvian Andes (Calca, Cusco).
Ingrid Hall
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

UM ESTUDO DAS ANALOGIAS SOBRE EQUILÍBRIO QUÍMICO NOS LIVROS APROVADOS PELO PNLEM 2007

open access: yesEnsaio Pesquisa em Educação em Ciências
Este artigo descreve uma análise crítica das analogias apresenta das para o tópico de equilíbrio químico pelos livros de Química aprova dos pelo PNLEM 2007. Foram localizadas oito analogias, sendo uma delas repetida.
Wilmo Ernesto Francisco Junior   +3 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

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