Results 31 to 40 of about 271,989 (296)

Constitutional Analogies in the International Legal System [PDF]

, 2003
This Article explores issues at the frontier of international law and constitutional law. It considers five key structural and systemic challenges that the international legal system now faces: (1) decentralization and disaggregation; (2) normative and ...
Laurence R. Helfer, See Hathaway, Colum J Transnat&apos, Judith Goldstein, Ellen Lutz &, Chayes &, Kal Raustiala, See George, See David, Alan O Sykes, See Atik, Raustialia, See Andrew Moravcsik, See Jeffrey, J Peter, See Philip, A, Helfer, E G See, Ernstulrich Petersmann, J Nw, &, L Pepp, Stein   +23 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Uso espontâneo de analogias por professores de biologia e o uso sistematizado de analogias: que relação? The spontaneous use of analogies by biology teachers and the use of systemic analogies: which works?

Ciência & Educação, 2003
Vários autores têm refletido sobre o papel das metáforas e das analogias tanto na produção do conhecimento em áreas específicas do saber, quanto na construção do conhecimento no âmbito do desenvolvimento de uma disciplina escolar.
Daniela Frigo Ferraz, Eduardo Adolfo Terrazzan   +1 more
doaj   +1 more source

Structured analogies for forecasting [PDF]

When people forecast, they often use analogies but in an unstructured manner. We propose a structured judgmental procedure that involves asking experts to list as many analogies as they can, rate how similar the analogies are to the target situation, and
J. Scott Armstrong, Kesten C. Green
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Analogies in the historical development of IHL (1864–2001)

International Review of the Red Cross
Analogies appear to permeate the entire domain of international humanitarian law (IHL), but as an independent subject of inquiry, they remain largely overlooked within IHL scholarship.
Pauline Lesaffre
doaj   +1 more source

Using Visual Analogies To Teach Introductory Statistical Concepts

Numeracy, 2017
Introductory statistical concepts are some of the most challenging to convey in quantitative literacy courses. Analogies supplemented by visual illustrations can be highly effective teaching tools.
Jessica S. Ancker, Melissa D. Begg
doaj   +1 more source

Gravito-electromagnetic analogies

, 2014
We reexamine and further develop different gravito-electromagnetic (GEM) analogies found in the literature, and clarify the connection between them. Special emphasis is placed in two exact physical analogies: the analogy based on inertial fields from the
A Balakin, A Komar, A Matte, A Papapetrou, C Cherubini, C Corda, C Lozanovski, C Lozanovski, C Tsagas, C Tsagas, CBG McIntosh, Charles W Misner, D Bini, D Bini, D Bini, D Lynden-Bell, D Mason, D Nichols, David C Kay, DH Tchrakian, E Massa, E Massa, E Massa, EG Harris, FAE Pirani, FAE Pirani, FC Mena, G Rizzi, G Rizzi, GFR Ellis, GFR Ellis, H Elst Van, H Goldstein, I Ciufolini, I Ciufolini, I Ciufolini, I Ciufolini, J Barrow, J Costa, J Garecki, J Kaplan, JJ Ferrando, JM Bardeen, JM Bardeen, JMM Senovilla, José Natário, José Natário, K Nordtvedt, K Nordtvedt, Kip S Thorne, L Bel, L Bel, L Bel, L Iorio, L Landau, L Wylleman, L Wylleman, L. Filipe O. Costa, LF Costa, M Mathisson, M Nouri-Zonoz, M Soffel, ML Ruggiero, ML Ruggiero, N Drukker, Naresh Dadhich, O Semerák, O Semerák, O Semerák, O Semerák, PKS Dunsby, QG Bailey, R Maartens, RM Wald, RM Wald, RT Jantzen, S Deser, S Gralla, S Hawking, SJ Clark, SM Carroll, SW Hawking, T Damour, TW Baumgarte, TW Murphy Jr, W Campbell, W Campbell, WB Bonnor, WG Dixon, WG Dixon   +89 more
core   +1 more source