Results 61 to 70 of about 26,307 (265)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Pensamiento analógico y construcción de un modelo molecular para la materia [PDF]

open access: yesRevista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2007
Firstly, in this paper a theoretical scheme on the mechanisms of the analogical thinking in science education is summarised. Secondly, the degree of understanding reached by a group of students about the analogies used in class on the molecular model is ...
Oliva, J.Mª., Aragón, Mª.M.
doaj  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Innovative teaching and technology in the service of science: Recruiting the next generation of STEM students

open access: yesJournal of the Scholarship of Teaching and Learning, 2012
This article examines innovative approaches to augmenting science lessons taught in middle and high school, with special emphasis on theimportance of the early teen years, when experiences both in and out of school have significant impact on career ...
Thomas McNally
doaj   +2 more sources

Typological Parallels and Differences in the Poetry of Taras Shevchenko and Slovak Romantic Poets (Samo Chalupka, Andrej Sládkovič, Janko Kráľ, Ján Botto) [PDF]

open access: yesSlovenska Literatura, 2020
The paper aims at identifying possible typological overlaps between the works of Slovak romantic poets (Samo Chalupka, Andrej Sládkovič, Janko Kráľ, Ján Botto) and the most prominent Ukrainian writer Taras Shevchenko.
Oleksandr Boroň
doaj  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Analogies as a potential for expressing creativity at different levels [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini
People living in the modern world face an increasing number of serious problems, the solution to which requires a creative approach. Therefore, the issue of creativity development and the factors that influence it are becoming increasingly important, as ...
Cvjetinović Vesna Z.   +1 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

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