Results 101 to 110 of about 4,816,806 (365)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Analysis and application of minimum variance discrete time system identification [PDF]

open access: yes
An on-line minimum variance parameter identifier is developed which embodies both accuracy and computational efficiency. The formulation results in a linear estimation problem with both additive and multiplicative noise.
Kaufman, H., Kotob, S.
core   +4 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Housing Attribute Preferences in Bandung City

open access: yesDimensi: Journal of Architecture and Built Environment
Each generation encounters distinct social, economic, cultural, and techno­logical contexts specific to their era. Moreover, their lifestyles vary, resulting in disparate housing preferences.
Ilma Nurfadlilawati, Hanson E Kusuma
doaj   +1 more source

Sensitivity Analysis of Steel Box-Section Girders. [PDF]

open access: yes, 2013
The paper deals with the load–carrying capacity stochastic variance based sensitivity analysis of thin–walled box–section girder subjected to pure bending. The lower– and uppe-r-bound load–capacity estimation is performed. The methodology is based on the
Kotełko, Maria, Lis, Paweł
core  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Welding Connection Strenght of Aluminium 1100 with Current Variations at Metal Inert Gas (MIG) Welding Process

open access: yesJurnal Energi Dan Manufaktur, 2012
In order to design of machine or building constructions use of welding connection, there are many factors should beconsidered such as skill, knowledge about welding procedures and material characteristics.
I Dewa Made Krishna Muku
doaj  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

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