Results 31 to 40 of about 34,658 (254)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Mechanical Foundations of the Generalized Second Law and the Irreversibility Principle

open access: yesFoundations
We follow the Boltzmann-Clausius-Maxwell (BCM) proposal to establish the generalized second law (GSL) that is applicable to a system of any size, including a single particle system as our example establishes, and that supercedes the celebrated second law
Purushottam Das Gujrati
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Approximate analytical and numerical solutions of a nonlinear boundary value problem in fluid mechanics based on symmetry reduction

open access: yesPartial Differential Equations in Applied Mathematics, 2020
This work presents applications of the Liesymmetry method to a boundary value problem (BVP) of the governing equations in fluid mechanics. The Wu differential characteristic set algorithm is used to obtain a group of multi-parameter symmetries for the ...
Litao Gai, Mingchu Li, Bilige Sudao
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Dirac Brackets and Time-Dependent Constraints

open access: yesUniverse
We provide a simultaneous derivation of the Dirac bracket and of the equations of motion for second-class constrained systems when the constraints are time-dependent.
Nuno Barros e Sá
doaj   +1 more source

Advances in CALIPSO (IIR) cirrus cloud property retrievals – Part 2: Global estimates of the fraction of cirrus clouds affected by homogeneous ice nucleation [PDF]

open access: yesAtmospheric Chemistry and Physics
Cirrus clouds can form through two ice nucleation pathways (homo- and heterogeneous ice nucleation; henceforth hom and het, respectively) that result in very different cloud physical and radiative properties.
D. L. Mitchell, A. Garnier
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Regional Characterization of Deep Convective Clouds for Enhanced Imager Stability Monitoring and Methodology Validation

open access: yesRemote Sensing
The NASA CERES project conducts an independent assessment of the calibration stability of MODIS and VIIRS reflective solar bands to ensure consistency in CERES-derived clouds and radiative flux products.
David Doelling   +4 more
doaj   +1 more source

Finite element simulation of barge impact into a rigid wall

open access: yesAlexandria Engineering Journal, 2014
The forces and locations of inland barge impacts currently control the design specifications for lock walls. This has resulted in a significant increase in the final construction costs of these walls.
H.W. Leheta   +2 more
doaj   +1 more source

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