Results 71 to 80 of about 2,834,111 (323)

Mechanics Property Analysis of High-resistance Steel Wire Mesh in Slope Flexible Stabilization System

Chemical Engineering Transactions, 2015
This paper aims at studying deformation mechanism and mechanics property of high-resistance steel wire mesh in slope flexible stabilization system and makes theoretical analysis under unilateral tension, and the analytical results are compared with the ...
G.S. Wang, S.Q. Shi, M. Wang
doaj   +1 more source

The creative mechanism: An analytic model

Mathematical Modelling, 1985
AbstractThis paper presents a model for the mechanism of creativity which is derived from the concepts and conclusions of analytic psychology. Creativity is presented as the intended goal of sexual staging with each of the three stages oral, anal, and genital yielding a distinct psychic subsystem which is integral to the mechanism.
openaire   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Analyzing the Motion of Symmetric Tops Without Recurring to Analytical Mechanics

Frontiers in Physics, 2020
Characterizing the dynamics of heavy symmetric tops is essential in several fields of theoretical and applied physics. Accordingly, a series of approaches have been developed to describe their motion.
Zsolt I. Lázár, Antal Jakovác, Péter Hantz, Péter Hantz   +3 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

The Foundations of Dynamics and Dadourian's Analytical Mechanics [PDF]

, 1917
H. M. Dadourian
openalex   +2 more sources

Modeling and Analysis of Aeroelasticity and Sloshing for Liquid Rocket

IEEE Access, 2019
In this paper, based on the advantages of Newtonian mechanics method, mixed coordinate method, and analytical mechanics method, the dynamic model of rigid-aeroelasticity-sloshing coupling is established for longitudinal vibration and liquid fuel sloshing,
Dewei Zhang, Hui Qi, Jiangtao Xu, Ya Yang, Bangsheng Fu   +4 more
doaj   +1 more source

Dadourian's Analytical Mechanics and the Principles of Dynamics [PDF]

Science, 1914
n ...
openaire   +4 more sources

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source