Results 71 to 80 of about 3,397,715 (333)

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Numerical approach to the Schrodinger equation in momentum space

open access: yes, 2009
The treatment of the time-independent Schrodinger equation in real-space is an indispensable part of introductory quantum mechanics. In contrast, the Schrodinger equation in momentum space is an integral equation that is not readily amenable to an ...
Christopher R. Jamell   +9 more
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Jacobi Elliptic Functions and the Complete Solution to the Bead on the Hoop Problem

open access: yes, 2012
Jacobi elliptic functions are flexible functions that appear in a variety of problems in physics and engineering. We introduce and describe important features of these functions and present a physical example from classical mechanics where they appear: a
Baker, Thomas E., Bill, Andreas
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Neural network-based snow depth retrieval from AMSR-2 brightness temperatures using ICESat-2 measurement as ground truth

open access: yesFrontiers in Remote Sensing
IndroductionEstimating snow depth over Arctic sea ice is essential for understanding climate processes and supporting operational forecasting. Previous work has demonstrated the use of lidar backscattering pathlength moments from Ice, Cloud, and land ...
Sunny Sun-Mack   +4 more
doaj   +1 more source

Acoustic emission from a growing crack [PDF]

open access: yes
An analytical method is being developed to determine the signature of an acoustic emission waveform from a growing crack and the results of this analysis are compared to experimentally obtained values.
Jacobs, Laurence J.
core   +1 more source

Onset of Fokker-Planck dynamics within a Closed Finite Spin System

open access: yes, 2012
Relaxation according to Fokker-Planck equations is a standard scenario in classical statistical mechanics. It is however not obvious how such an equilibration may emerge within a closed, finite quantum system.
Gemmer, Jochen   +2 more
core   +1 more source

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