Results 81 to 90 of about 3,321,873 (370)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Modeling thermo-mechanical fatigue for rolling die under continuous casting process

Results in Engineering
In the continuous casting process, the rolling die is exposed to non-steady stress conditions that can initiate thermo-mechanical fatigue damage. Understanding the rolling die failure mechanism is essential in metal-forming industries.
Mesay Alemu Tolcha, Hirpa Gelgele Lemu
doaj   +1 more source

Analytical Elastostatic Contact Mechanics of Highly-Loaded Contacts of Varying Conformity

Lubricants, 2020
In applications requiring high load carrying capacity, conforming contacting pairs with a relatively large contact footprint are used. These include circular arc, Novikov, and Wildhaber gears found, for example, in helicopter rotors.
Patricia M. Johns-Rahnejat, Nader Dolatabadi, Homer Rahnejat   +2 more
doaj   +1 more source

Self-Similar Crossover in Statistical Physics

, 2000
An analytical method is advanced for constructing interpolation formulae for complicated problems of statistical mechanics, in which just a few terms of asymptotic expansions are available.
Baker, Baker, Benettin, Blote, Edwards, Fisher, Girardeau, Gluzman, Irving, Lieb, Muthukumar, Muthukumar, Nakamura, Oguchi, S Gluzman, Saff, Selyugin, Simon, Takahashi, Takahashi, Theodorakopoulos, V.I Yukalov, Von Meyenn, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalova, Čizek   +34 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Modeling and Analysis of Aeroelasticity and Sloshing for Liquid Rocket

IEEE Access, 2019
In this paper, based on the advantages of Newtonian mechanics method, mixed coordinate method, and analytical mechanics method, the dynamic model of rigid-aeroelasticity-sloshing coupling is established for longitudinal vibration and liquid fuel sloshing,
Dewei Zhang, Hui Qi, Jiangtao Xu, Ya Yang, Bangsheng Fu   +4 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Acoustic emission from a growing crack [PDF]

An analytical method is being developed to determine the signature of an acoustic emission waveform from a growing crack and the results of this analysis are compared to experimentally obtained values.
Jacobs, Laurence J.
core   +1 more source

Numerical approach to the Schrodinger equation in momentum space

, 2009
The treatment of the time-independent Schrodinger equation in real-space is an indispensable part of introductory quantum mechanics. In contrast, the Schrodinger equation in momentum space is an integral equation that is not readily amenable to an ...
Christopher R. Jamell, Dennery P., Dirac P. A. M., Griffiths D. J., Landau L. D., Landau R. H., Merzbacher E., Sakurai J. J., William A. Karr, Yogesh N. Joglekar   +9 more
core   +1 more source