Results 121 to 130 of about 459 (187)

ANALYTICAL QUALITY BY DESIGN (AQBD) IN THE DEVELOPMENT AND VALIDATION OF CHROMATOGRAPHIC METHODS FOR FIXED-DOSE COMBINATIONS: A COMPREHENSIVE REVIEW

The paradigm of pharmaceutical analysis is undergoing a critical transition from traditional empirical Quality by Testing (QbT) frameworks to systematic, risk-based methodologies encapsulated by the Analytical Quality by Design (AQbD) initiative. This shift is particularly crucial for Fixed-Dose Combinations (FDCs), where the simultaneous estimation of
openaire   +2 more sources

Analytical Quality by Design (AQBD) Assisted Development and Validation of HPTLC Method for Estimation of Rottlerin in Topical Patch Formulation

Pharmacognosy Research, 2023
Kaumudee Bodas, Vaibhav M Shinde, Deshmukh Vishal, Deshmukh Sheetal   +3 more
openaire   +1 more source

A Survey on the Implementation of Analytical Quality by Design in Method Development in the Pharmaceutical Industries of Southeast Brazil: Challenges and Opportunities. [PDF]

Ther Innov Regul Sci
Claro BC, Condado EF, Prado LD.
europepmc   +1 more source

Development of an AQbD-guided sustainable RP-HPLC method for simultaneous quantification of saracatinib and rapamycin in lipid-polymer hybrid nanocarriers. [PDF]

RSC Adv
Angolkar M, Paramshetti S, Patil D, K M AS, Osmani RAM, Gangadharappa HV, Fatease AA, Alamri AH, Hani U.   +8 more
europepmc   +1 more source

Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Arformoterol Tartrate Inhalation Solution Dosage Form via RP-HPLC. [PDF]

ACS Omega
Alluri NR, Bandlamudi MR, Kuppusamy S, Morais SR.   +3 more
europepmc   +1 more source

From design space to green space: an analytical quality by design-assisted high-performance liquid chromatography method for the quantification of triple-combination antihypertensive drugs. [PDF]

BMC Chem
Yenduri S, Yogaraj P, Koppuravuri NP.
europepmc   +1 more source

Analytical Quality-by-Design-Based Chaotropic Chromatography Method for the Determination of Bupropion and Its Impurities [PDF]

A novel chaotropic chromatography method, developed using Analytical Quality-by-Design (AQbD) principles, is presented for the quantitative determination of bupropion and its impurities.
Yannis, Dotsikas, Malenović, Anđelija, Kostas, Gkountanas   +2 more
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Green RP-HPLC method for estimation of trigonelline: AQbD based development, validation, and application to nanoformulations. [PDF]

BMC Chem
Kothapalli P, Vasanthan M.
europepmc   +1 more source

Reverse Phase High Performance Liquid Chromatography Method for the Estimation of Mangiferin in Nano Formulations: Development and Optimization by Analytical Quality-by-Design. [PDF]

ACS Omega
Kamath AP, Kumar L, Mutalik S, Nayak PG, Nandakumar K.   +4 more
europepmc   +1 more source

DEVELOPMENT AND VALIDATION OF A STABILITY-INDICATING HPTLC METHOD FOR VERAPAMIL ANALYSIS USING THE AQBD APPROACH [PDF]

Objective: To develop selective, precise and accurate High Performance Thin Layer Chromatography (HPTLC) method for forced degradation study of Verapamil by implementing AQbD (Analytical quality by design) approach. To optimize chromatographic conditions
PRAJAPATI, DHRUVI, BADGUJAR, GAYATRI S.
core