Results 101 to 110 of about 1,038 (200)
Journal of Saudi Chemical SocietyThe goal of this study was to use High performance liquid chromatography (HPLC) with an Analytical Quality by Design (AQbD) approach to measure the amount of caffeine in selected coffee samples available in the local Jazan market in Saudi Arabia.
Asim Najmi +9 more
doaj +1 more source
Improving the biopharmaceutical attributes of mangiferin using vitamin E-TPGS co-loaded self-assembled phosholipidic nano-mixed micellar systems [PDF]
, 2018 The current research work encompasses the development, characterization, and evaluation of self-assembled phospholipidic nano-mixed miceller system (SPNMS) of a poorly soluble BCS Class IV xanthone bioactive, mangiferin (Mgf) functionalized with co ...
Gaspar, Balan Louis +5 more
core +2 more sources
OPTIMASI DAN VALIDASI METODE KLT-DENSITOMETRI PADA ANALISIS FARMASI : TINJAUAN KRITIS DAN STUDI KOMPARATIF [PDF]
Kromatografi Lapis Tipis (KLT) Densitometri atau High Performance Thin Layer Chromatography (HPTLC) tetap menjadi metode analisis instrumental yang vital, terutama di negara berkembang, karena efisiensi biaya dan kemampuannya menangani banyak sampel ...
Anggrainy, Dian Sari +6 more
core +1 more source
Journal of Taibah University for ScienceThis study developed a stability-indicating RP-HPLC method for quantifying azelnidipine and chlorthalidone in fixed-dose formulations using Analytical Quality by Design (AQbD) principles.
Rajvi Agrawal, Rajendra Kotadiya
doaj +1 more source
Application of the concept of design space in method development for the determination of contaminants in soil [PDF]
Proceedings of the Estonian Academy of SciencesThe analysis of polycyclic aromatic hydrocarbons and polychlorinated biphenyls is an important topic in environmental analysis, and several analysis procedures have already been proposed.
Jelena Jurjeva, Mihkel Koel
doaj +1 more source
, 2015 Quality by Design (QbD) principles were implemented in RP-HPLC method development for the analysis of dissolution samples of immediate release film-coated tablets. Critical method variables and critical method attributes were identified. After the initial risk assessment, a DoE (design of experiments) study was performed to investigate the impact of ...
Bartolec, Maja +3 more
openaire +2 more sources
Регуляторные исследования и экспертиза лекарственных средствINTRODUCTION. In 2023, the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) published a new Guideline on Analytical Procedure Development (ICH Q14) and a revised version of the Guideline on ...
A. V. Fetisova +4 more
doaj +1 more source
Reviews in Analytical ChemistryThe study presents the development of a novel, sustainable, and analytical quality by design (AQbD) driven RP-HPLC method to simultaneously identify disodium edetate in eye drops and its degradation products.
Alanazi Tahani Y. A. +5 more
doaj +1 more source
Application of Qbd Principles to Develop and Validate a Method for Cinacalcet Determination in Api and Its Dosage Form [PDF]
Introduction: Cinacalcet Hcl [CIN] is used to treat hyperthyroidism and hypercalcisim. and improves the sensitivity of calcium receptors on parathyroid cells to reduce parathyroid harmone levels and hence decrease serum calcium levels. It also has a role
A.Srinija, Sneha Takur, R.Prasanthi, Buggana Siva Jyothi, R.Swetha Sri
core +2 more sources
A QbD-based stability-indicating RP-HPLC method for larotrectinib: degradation kinetics and integrated white, green, and blue analytical assessment [PDF]
Background: Larotrectinib, a selective TRK inhibitor, received FDA approval on April 10, 2025, for treating solid tumors with NTRK gene fusions. Despite its therapeutic significance, no RP-HPLC method using a Quality-by-Design (QbD) framework has been ...
Adikay, Sreedevi, P. N. S, Syamala
core +2 more sources