Results 91 to 100 of about 62,955,482 (158)

AQbD-assisted HPLC method for simultaneous determination of methylparaben and propylparaben in liquid oral dosage forms. [PDF]

Sci Rep
Darraj R, Haroun M, Abbood A, Alghoraibi I.   +3 more
europepmc   +1 more source

Analytical Quality by Design (AQbD) in HPLC Method Development: A Comprehensive Review of Principles, Tools, Regulatory Framework, and Emerging Applications

Over the past two decades, pharmaceutical analytical science has undergone a quiet but consequential transformation in how methods are conceived, developed, and sustained across their operational lifetimes. The emergence of Analytical Quality by Design (AQbD) as a governing philosophy — rather than a procedural formality or a regulatory concession ...
openaire   +2 more sources

A Survey on the Implementation of Analytical Quality by Design in Method Development in the Pharmaceutical Industries of Southeast Brazil: Challenges and Opportunities. [PDF]

Ther Innov Regul Sci
Claro BC, Condado EF, Prado LD.
europepmc   +1 more source

UNVEILING METHOD OPERABLE DESIGN SPACE FOR THE QUANTIFICATION OF PIOGLITAZONE AND VILDAGLIPTIN BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY AND ITS FORCED DEGRADATION STUDIES: ANALYTICAL QUALITY BY DESIGN APPROACH

Objective: To develop and validate an environmentally friendly RP-HPLC method for the simultaneous determination of pioglitazone and vildagliptin using Analytical Quality by Design (AQbD) principles with Central Composite Design (CCD), ensuring ...
DEVI SWAPNA PV, SARAVANAN G
core  

Development of an AQbD-guided sustainable RP-HPLC method for simultaneous quantification of saracatinib and rapamycin in lipid-polymer hybrid nanocarriers. [PDF]

RSC Adv
Angolkar M, Paramshetti S, Patil D, K M AS, Osmani RAM, Gangadharappa HV, Fatease AA, Alamri AH, Hani U.   +8 more
europepmc   +1 more source

Development and validation of methodology for antibiotic analysis using the Analytical Quality by Design (AQbD) approach

Diante de muitas ameaças crescentes aos ecossistemas aquáticos, uma das mais preocupantes com as quais a humanidade se depara é o surgimento e desenvolvimento de bactérias resistentes a antibióticos.
Silva, Mirelle Lopes da [UNIFESP]
core  

AQbD-driven RP-HPLC method for complete resolution of pantoprazole regioisomeric impurities with integrated multi-dimensional sustainability assessment. [PDF]

BMC Chem
Gaddam TR, Nallagondu CGR, Masani NK, Kareti AD, Vemulapati HR, Chanduluru HK.   +5 more
europepmc   +1 more source

From design space to green space: an analytical quality by design-assisted high-performance liquid chromatography method for the quantification of triple-combination antihypertensive drugs. [PDF]

BMC Chem
Yenduri S, Yogaraj P, Koppuravuri NP.
europepmc   +1 more source

Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Arformoterol Tartrate Inhalation Solution Dosage Form via RP-HPLC. [PDF]

ACS Omega
Alluri NR, Bandlamudi MR, Kuppusamy S, Morais SR.   +3 more
europepmc   +1 more source

Evaluation of Method "Whiteness" in the Stability Analysis of Dexamethasone and PVP-I Ophthalmic Suspensions: Synergizing LC-MS/MS, In Silico Toxicology, and AGREE/GAPI Metrics. [PDF]

Biomed Chromatogr
Mandal L, Vemuri PK, Malothu N, Tiwari S.   +3 more
europepmc   +1 more source