Results 91 to 100 of about 459 (187)
Background: Pharmaceutical analytical methods are very important for ensuring drug quality. However traditional methods often rely on trial and error. This can lead to methods that're not very robust or flexible. Analytical Quality by Design (AQbD) is an approach. It uses science-based principles for analytical methods.
Manish Kumar Barala +2 more
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Frontiers in Analytical ScienceIntroductionA reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the quantitation of nevirapine (NVP) in bulk drug, commercial tablets, and niosome formulations using an Analytical Quality by Design ...
Bwalya A. Witika, Roderick B. Walker
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A Mini Overview of Analytical Quality by Design (AQbD)
A methodical, science- and risk-based approach to pharmaceutical development, Quality by Design (QbD) emphasizes incorporating quality into goods rather than depending just on end product testing. Through standards like ICH Q8 (Pharmaceutical Development), Q9 (Quality Risk Management), and Q10 (Pharmaceutical Quality System), regulatory bodies ...
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Analytical quality by design (aqbd) approach for an hplc method development and valiadtion [PDF]
Magistrsko delo se osredotoča na razvoj in validacijo HPLC metode za določanje sorodnih substanc v raztopini klorheksidin diglukonata z uporabo pristopa Analytical Quality by Design (AQbD).
Pavlović, Marko
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Journal of Saudi Chemical SocietyThe goal of this study was to use High performance liquid chromatography (HPLC) with an Analytical Quality by Design (AQbD) approach to measure the amount of caffeine in selected coffee samples available in the local Jazan market in Saudi Arabia.
Asim Najmi +9 more
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Review of the article „The Impact of Analytical Quality by Design (AQbD) in the Method Development of Liquid Chromatography for Quality Control of Pharmaceuticals: A Review“, verified by Publons, Web of Science [PDF]
, 2019 The objective of this review article is to provide a comprehensive understanding on different steps of AQbD, along with their concern ICH guidelines.
Jovanović, Tamara
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, 2015 Quality by Design (QbD) principles were implemented in RP-HPLC method development for the analysis of dissolution samples of immediate release film-coated tablets. Critical method variables and critical method attributes were identified. After the initial risk assessment, a DoE (design of experiments) study was performed to investigate the impact of ...
Pranjić, Josip +2 more
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Quality by Design in the development of hydrophilic interaction liquid chromatography method with gradient elution for the analysis of olanzapine [PDF]
, 2017 This paper deals with the development of hydrophilic interaction liquid chromatography (HILIC) method with gradient elution, in accordance with Analytical Quality by Design (AQbD) methodology, for the first time.
Jančić-Stojanović, Biljana +3 more
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Application of the concept of design space in method development for the determination of contaminants in soil [PDF]
Proceedings of the Estonian Academy of SciencesThe analysis of polycyclic aromatic hydrocarbons and polychlorinated biphenyls is an important topic in environmental analysis, and several analysis procedures have already been proposed.
Jelena Jurjeva, Mihkel Koel
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International Journal of Pharmaceutical Research and ApplicationsAnalytical Quality by Design (AQbD) applies Quality by Design principles to analytical method development, aiming to design methods that are robust, well-understood, and life cycle managed. Herbicide residue analysis (monitoring active compounds and metabolites in formulations, food, soil, and water) presents challenges of trace-level detection, matrix
Wafa T Wafa T +3 more
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