Results 131 to 140 of about 54,411 (234)

Anaphase-Promoting Complex [PDF]

, 2008
  +4 more sources

Functional specialization of the yeast Rho1 GTP exchange factors [PDF]

, 2012
Rho GTPases are regulated in complex spatiotemporal patterns that may be dependent, in part at least, on the multiplicity of their GTP exchange factors (GEFs).
Cundell, M., Gray, J., Johnston, G., Krause, S., McGhie, J., Poon, P., Price, C.   +6 more
core  

Retinoblastoma Pathway Dysregulation Causes DNA Methyltransferase 1 Overexpression in Cancer via MAD2-Mediated Inhibition of the Anaphase-Promoting Complex [PDF]

, 2007
Agoston T. Agoston, Pedram Argani, Angelo M. De Marzo, Jessica Hicks, William G. Nelson   +4 more
openalex   +1 more source

Meiosis-specific regulation of the anaphase-promoting complex

, 2006
Die Meiose ist ein spezialisierter Zellzyklus, der zum Ziel hat haploide Gameten aus diploiden Vorläuferzellen zu produzieren. Dafür erfolgen nach der prä-meiotischen DNA Replikation zwei aufeinanderfolgende Kernteilungen. In der ersten meiotischen Teilung erfolgt die Trennung der homologen Chromosomen.
openaire   +3 more sources

The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment. [PDF]

Dev Cell, 2023
Ledvin L, Gassaway BM, Tawil J, Urso O, Pizzo D, Welsh KA, Bolhuis DL, Fisher D, Bonni A, Gygi SP, Brown NG, Ferguson CJ.   +11 more
europepmc   +1 more source

Interphase APC/C–Cdc20 inhibition by cyclin A2–Cdk2 ensures efficient mitotic entry

Nature Communications, 2016
The Anaphase Promoting Complex/Cyclosome (APC/C) and its co-activator Cdc20 regulate mitotic progression, but both are also present in interphase. Here Hein and Nilsson show that Cyclin A2–CDK2 phosphorylates Cdc20 to inhibit APC/C–Cdc20 activity during ...
Jamin B. Hein, Jakob Nilsson
doaj   +1 more source

Mcm10 proteolysis initiates before the onset of M-phase

BMC Cell Biology, 2010
Background Mcm10 protein is essential for initiation and elongation phases of replication. Human cells proteolyze Mcm10 during mitosis, presumably to ensure a single round of replication. It has been proposed that anaphase promoting complex ubiquitinates
Khan Muntaz, Sharma Aparna, Kaur Manpreet, Kar Ananya, Saxena Sandeep   +4 more
doaj   +1 more source

KEN-Box-dependent Degradation of the Bub1 Spindle Checkpoint Kinase by the Anaphase-promoting Complex/Cyclosome [PDF]

, 2006
Wei Qi, Hongtao Yu
openalex   +1 more source

Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C

Nature Communications, 2019
During the spindle assembly checkpoint, the activity of the anaphase promoting complex/cyclosome (APC/C) is repressed, yet cyclin A2 evades the checkpoint and is targeted for degradation.
Suyang Zhang, Thomas Tischer, David Barford   +2 more
doaj   +1 more source

Lactate regulates cell cycle by remodelling the anaphase promoting complex. [PDF]

Nature, 2023
Liu W, Wang Y, Bozi LHM, Fischer PD, Jedrychowski MP, Xiao H, Wu T, Darabedian N, He X, Mills EL, Burger N, Shin S, Reddy A, Sprenger HG, Tran N, Winther S, Hinshaw SM, Shen J, Seo HS, Song K, Xu AZ, Sebastian L, Zhao JJ, Dhe-Paganon S, Che J, Gygi SP, Arthanari H, Chouchani ET.   +27 more
europepmc   +1 more source