Results 151 to 160 of about 53,781 (249)

Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit

Nature Communications, 2016
The activity of the anaphase-promoting complex/cyclosome (APC/C) needs to be regulated in time and space to perform different functions. Here the authors show that Spd2 localizes the APC/C activator Fzr at the centrosomes to promote optimal APC/C ...
Francesco Meghini, Torcato Martins, Xavier Tait, Kazuyuki Fujimitsu, Hiroyuki Yamano, David M. Glover, Yuu Kimata   +6 more
doaj   +1 more source

Lactate regulates cell cycle by remodelling the anaphase promoting complex. [PDF]

Nature, 2023
Liu W, Wang Y, Bozi LHM, Fischer PD, Jedrychowski MP, Xiao H, Wu T, Darabedian N, He X, Mills EL, Burger N, Shin S, Reddy A, Sprenger HG, Tran N, Winther S, Hinshaw SM, Shen J, Seo HS, Song K, Xu AZ, Sebastian L, Zhao JJ, Dhe-Paganon S, Che J, Gygi SP, Arthanari H, Chouchani ET.   +27 more
europepmc   +1 more source

Cell Cycle-dependent Expression of Centrosomal Ninein-like Protein in Human Cells Is Regulated by the Anaphase-promoting Complex [PDF]

, 2007
Yang Wang, Qimin Zhan
openalex   +1 more source

Parkinson's Disease and Cancer: Mechanistic Insights and Therapeutic Opportunities From Cancer Neuroscience

MedComm – Oncology, Volume 4, Issue 4, December 2025.
Parkinson's disease (PD) and glioma are neurological disorders with distinct and even opposing mechanisms: α‐synuclein deposition and neuronal loss in PD versus glial cell malignancy in glioma. Despite these differences, their contrasting pathologies highlight multiple therapeutic targets.
Tianli Pan, Lin Yuan, Ruoyang Zhao, Liting Lu, Yinghao Zhi, Yuying Li, Min Wu, Yongye Huang   +7 more
wiley   +1 more source

Anaphase-Promoting Complex [PDF]

, 2008
  +4 more sources

The Anaphase-Promoting Complex/Cyclosome Is a Cellular Ageing Regulator. [PDF]

Int J Mol Sci, 2022
Hu X, Jin X, Cao X, Liu B.
europepmc   +1 more source

Identification of genomic regions associated with partial resistance to Aphanomyces root rot in pea

The Plant Genome, Volume 18, Issue 4, December 2025.
Abstract Root rot caused by Aphanomyces euteiches is a major concern in pea (Pisum sativum L.). The lack of other effective control strategies makes crucial the development of resistant varieties. Although partial resistance has been reported, its quantitative inheritance, the association of resistance‐linked genomic regions with unfavorable agronomic ...
Sara Rodriguez‐Mena, Maria Carlota Vaz Patto, Susana Trindade Leitão, Diego Rubiales, Mario González   +4 more
wiley   +1 more source

Anaphase-Promoting Complex Subunit 1 Associates with Bone Mineral Density in Human Osteoporotic Bone. [PDF]

Int J Mol Sci, 2023
Malavašič P, Polajžer S, Lovšin N.
europepmc   +1 more source

Deletion of the Mis12C‐Binding Domain of CENP‐C Promotes Chromosomal Aneuploidy in Cutaneous Squamous Cell Carcinoma

Cancer Science, Volume 116, Issue 12, Page 3532-3539, December 2025.
M12BD deficiency increases a chromosomal aneuploidy, particularly trisomy of chromosomes 6 and 10. ABSTRACT CENP‐C, an essential component of the kinetochore, connects centromeric chromatin to the outer kinetochore, and thereby ensures accurate chromosome segregation.
Megumi Saito, Kazuhiro Okumura, Yurika Tokunaga, Sora Tanaka, Keisuke Otoyama, Yoshinori Hasegawa, Masatoshi Hara, Masakazu Hashimoto, Toshihiko Fujimori, Tatsuo Fukagawa, Yuichi Wakabayashi   +10 more
wiley   +1 more source

Identification and sequencing of temperature sensitive alleles of the Anaphase Promoting Complex component mat-3 in C. elegans. [PDF]

MicroPubl Biol, 2023
Maniates KA, Zuo Y, Flanagan K, Halim SG, Kane A, Singson A.   +5 more
europepmc   +1 more source