Results 161 to 170 of about 282,951 (269)

Interphase APC/C–Cdc20 inhibition by cyclin A2–Cdk2 ensures efficient mitotic entry

Nature Communications, 2016
The Anaphase Promoting Complex/Cyclosome (APC/C) and its co-activator Cdc20 regulate mitotic progression, but both are also present in interphase. Here Hein and Nilsson show that Cyclin A2–CDK2 phosphorylates Cdc20 to inhibit APC/C–Cdc20 activity during ...
Jamin B. Hein, Jakob Nilsson
doaj   +1 more source

Hsl1p, a Swe1p Inhibitor, Is Degraded via the Anaphase-Promoting Complex [PDF]

, 2000
Janet L. Burton, Mark J. Solomon
openalex   +1 more source

Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C

Nature Communications, 2019
During the spindle assembly checkpoint, the activity of the anaphase promoting complex/cyclosome (APC/C) is repressed, yet cyclin A2 evades the checkpoint and is targeted for degradation.
Suyang Zhang, Thomas Tischer, David Barford   +2 more
doaj   +1 more source

Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit

Nature Communications, 2016
The activity of the anaphase-promoting complex/cyclosome (APC/C) needs to be regulated in time and space to perform different functions. Here the authors show that Spd2 localizes the APC/C activator Fzr at the centrosomes to promote optimal APC/C ...
Francesco Meghini, Torcato Martins, Xavier Tait, Kazuyuki Fujimitsu, Hiroyuki Yamano, David M. Glover, Yuu Kimata   +6 more
doaj   +1 more source

Anaphase-Promoting Complex Subunit 1 Associates with Bone Mineral Density in Human Osteoporotic Bone. [PDF]

Int J Mol Sci, 2023
Malavašič P, Polajžer S, Lovšin N.
europepmc   +1 more source

Two WD Repeat-containing TATA-binding Protein-associated Factors in Fission Yeast That Suppress Defects in the Anaphase-promoting Complex [PDF]

, 2001
Hiroshi Mitsuzawa, Hiroaki Seino, Fumiaki Yamao, Akira Ishihama   +3 more
openalex   +1 more source

Identification and sequencing of temperature sensitive alleles of the Anaphase Promoting Complex component mat-3 in C. elegans. [PDF]

MicroPubl Biol, 2023
Maniates KA, Zuo Y, Flanagan K, Halim SG, Kane A, Singson A.   +5 more
europepmc   +1 more source

Dysfunction of an Anaphase-Promoting Complex Subunit 8 Homolog Leads to Super-Short Petioles and Enlarged Petiole Angles in Soybean. [PDF]

Int J Mol Sci, 2023
Gao Y, Zhu J, Zhai H, Xu K, Zhu X, Wu H, Zhang W, Wu S, Chen X, Xia Z.   +9 more
europepmc   +1 more source

Functional specialization of the yeast Rho1 GTP exchange factors [PDF]

, 2012
Rho GTPases are regulated in complex spatiotemporal patterns that may be dependent, in part at least, on the multiplicity of their GTP exchange factors (GEFs).
Cundell, M., Gray, J., Johnston, G., Krause, S., McGhie, J., Poon, P., Price, C.   +6 more
core  

Control of division in Chlamydomonas by cyclin B/CDKB1 and the anaphase-promoting complex. [PDF]

PLoS Genet, 2022
Pecani K, Lieberman K, Tajima-Shirasaki N, Onishi M, Cross FR.   +4 more
europepmc   +1 more source