The role of the anaphase-promoting complex/cyclosome in plant growth [PDF]
Critical Reviews in Plant Sciences, 2015 The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit E3 ubiquitin ligase that plays a major role in the progression of the eukaryotic cell cycle.
de Freitas Lima, Marcelo +3 more
core +7 more sources
The Plant Anaphase-Promoting Complex/Cyclosome.
Annual Review of Cell and Developmental Biology, 2022 The anaphase-promoting complex/cyclosome (APC/C) represents a large multisubunit E3-ubiquitin ligase complex that controls the unidirectional progression through the cell cycle by the ubiquitination of specific target proteins, marking them for ...
Alex Willems, L. de Veylder
semanticscholar +4 more sources
Identification of anaphase promoting complex substrates in S. cerevisiae. [PDF]
PLoS ONE, 2012 The Anaphase-Promoting Complex/Cyclosome (APC/C) is an essential ubiquitin ligase that targets numerous proteins for proteasome-mediated degradation in mitosis and G1. To gain further insight into cellular pathways controlled by APC/C(Cdh1), we developed
Denis Ostapenko +2 more
doaj +5 more sources
The Arabidopsis anaphase-promoting complex/cyclosome subunit 8 is required for male meiosis. [PDF]
New Phytol, 2019 Summary Faithful chromosome segregation is required for both mitotic and meiotic cell divisions and is regulated by multiple mechanisms including the anaphase‐promoting complex/cyclosome (APC/C), which is the largest known E3 ubiquitin‐ligase complex and
Xu RY +7 more
europepmc +2 more sources
Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome [PDF]
eLifeE3 ubiquitin ligases engage their substrates via ‘degrons’ - short linear motifs typically located within intrinsically disordered regions of substrates.
Rohan Eapen +12 more
doaj +3 more sources
Anaphase-promoting complex/cyclosome regulates RdDM activity by degrading DMS3 in Arabidopsis. [PDF]
Proc Natl Acad Sci U S A, 2019 Significance RNA-directed DNA methylation (RdDM) is an important mechanism in the silencing of transposable elements in plants. The framework of RdDM has been well established, in which DNA polymerase IV (Pol IV) and Pol V act in upstream siRNA ...
Zhong S +10 more
europepmc +2 more sources
Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex. [PDF]
Molecular Biology of the Cell, 2014 The binucleate pathogen Giardia intestinalis is a highly divergent eukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint complex (MCC) proteins.
Cande, W Zacheus, Vicente, Juan-Jesus
core +3 more sources
Lactate regulates cell cycle by remodelling the anaphase promoting complex. [PDF]
Nature, 2023 Liu W +27 more
europepmc +2 more sources
Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription [PDF]
Nature Communications, 2022 Tissue-specific transcriptional activity is silenced in mitotic cells. Here the authors reveal a general phosphorylation-dependent mechanism of recognition for the anaphase-promoting complex (APC) substrates, and show that the APC targets ID2 during the ...
Sang Bae Lee +10 more
doaj +2 more sources
The Anaphase-Promoting Complex (APC) ubiquitin ligase affects chemosensory behavior in C. elegans [PDF]
PeerJ, 2016 The regulation of fundamental aspects of neurobiological function has been linked to the ubiquitin signaling system (USS), which regulates the degradation and activity of proteins and is catalyzed by E1, E2, and E3 enzymes. The Anaphase-Promoting Complex
Julia Wang +2 more
doaj +6 more sources