Results 211 to 220 of about 54,411 (234)

Mutations in ANAPC1, Encoding a Scaffold Subunit of the Anaphase-Promoting Complex, Cause Rothmund-Thomson Syndrome Type 1. [PDF]

Am J Hum Genet, 2019
Ajeawung NF, Nguyen TTM, Lu L, Kucharski TJ, Rousseau J, Molidperee S, Atienza J, Gamache I, Jin W, Plon SE, Lee BH, Teodoro JG, Wang LL, Campeau PM.   +13 more
europepmc   +1 more source

A novel human Cdh1 mutation impairs anaphase promoting complex/cyclosome activity resulting in microcephaly, psychomotor retardation, and epilepsy. [PDF]

J Neurochem, 2019
Rodríguez C, Sánchez-Morán I, Álvarez S, Tirado P, Fernández-Mayoralas DM, Calleja-Pérez B, Almeida Á, Fernández-Jaén A.   +7 more
europepmc   +1 more source

REGULATION OF THE ANAPHASE PROMOTING COMPLEX/CYCLOSOME IN DROSOPHILA FEMALE MEIOSIS

, 2013
Osamah Batiha
openalex   +1 more source

Anaphase-Promoting Complex 7 is a Prognostic Factor in Human Colorectal Cancer. [PDF]

Ann Coloproctol, 2017
Kim IY, Kwon HY, Park KH, Kim DS.
europepmc   +1 more source

Correction: A Minimal Anaphase Promoting Complex/Cyclosome (APC/C) in Trypanosoma brucei

PLoS ONE, 2013
doaj  

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Mitotic regulation of the anaphase-promoting complex

Cellular and Molecular Life Sciences, 2007
Orderly progression through mitosis is regulated by the anaphase-promoting complex/cyclosome (APC/C), a large multiprotein E3 ubiquitin ligase that targets key mitotic regulators for destruction by the proteasome. APC/C has two activating subunits, Cdc20 and Cdh1. The well-established view is that Cdc20 activates APC/C from the onset of mitosis through
D J, Baker, M M, Dawlaty, P, Galardy, J M, van Deursen   +3 more
openaire   +2 more sources

Enzymology of the Anaphase‐Promoting Complex

2005
The anaphase-promoting complex (APC) is an ubiquitin-protein ligase that promotes mitotic progression by catalyzing the ubiquitination of numerous proteins, including securin and cyclin. Its complex subunit composition and extensive regulation make the APC an active subject of investigation for both cell biologists and enzymologists.
Christopher W, Carroll, David O, Morgan
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Non-mitotic functions of the Anaphase-Promoting Complex

Seminars in Cell & Developmental Biology, 2011
The Anaphase-Promoting Complex or Cyclosome (APC/C) is an E3 ubiquitin ligase whose activation requires the binding of a cofactor, either Cdc20 or Cdh1. While APC/C-Cdc20 is a major player during mitotic exit, APC/C-Cdh1 plays a central role in maintaining quiescence and controlling the onset of DNA replication. In addition, APC/C-Cdh1 is essential for
Manuel, Eguren, Eusebio, Manchado, Marcos, Malumbres   +2 more
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The Anaphase-Promoting Complex: New Subunits and Regulators

Annual Review of Biochemistry, 1999
▪ Abstract  Ubiquitin-mediated proteolysis of cell cycle regulators is a crucial process during the cell cycle. The anaphase-promoting complex (APC) is a large, multiprotein complex whose E3-ubiquitin ligase activity is required for the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell ...
A M, Page, P, Hieter
openaire   +2 more sources