Results 101 to 110 of about 52,438 (267)

Modulating the activity of the APC/C regulator SISAMBA improves the sugar and antioxidant content of tomato fruits

Plant Biotechnology Journal, EarlyView.
Summary The Anaphase‐Promoting Complex/Cyclosome (APC/C) is an E3 ubiquitin ligase that plays a crucial role in ubiquitin‐dependent proteolysis of key cell cycle regulators, which is completed by the 26S proteasome. Previously, SAMBA, a plant‐specific regulator of the APC/C, was identified in Arabidopsis as a critical factor controlling organ size ...
Perla Novais de Oliveira, Leonardo Perez de Souza, Pedro Boscariol Ferreira, Jean Phillippe Mauxion, Luis Felipe Correa da Silva, Ana Isabela Chang, Marina de Lyra Soriano Saleme, Feng Zhu, Sara Selma García, Herman De Beukelaer, Marina C. M. Martins, Laise Rosado‐Souza, Lilian Ellen Pino, Norbert Bollier, Lázaro Eustáquio Pereira Peres, Klaas Vandepoele, Alain Goossens, Nathalie Gonzalez, Alisdair R. Fernie, Nubia Barbosa Eloy   +19 more
wiley   +1 more source

Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis.

PLoS Genetics, 2020
In mitosis and meiosis, chromosome segregation is triggered by the Anaphase-Promoting Complex/Cyclosome (APC/C), a multi-subunit ubiquitin ligase that targets proteins for degradation, leading to the separation of chromatids.
Damien Garrido, Mohammed Bourouh, Éric Bonneil, Pierre Thibault, Andrew Swan, Vincent Archambault   +5 more
doaj   +1 more source

Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset

Journal of Cell Biology, 2013
MAD2L2 is rapidly degraded by APC/CCDC20 at the onset of anaphase, allowing release of sequestered CDH1 to activate the dephosphorylated APC/C.
T. Listovsky, J. Sale
semanticscholar   +1 more source

RECQ4 restricts non‐interfering crossover formation to fine‐tune meiotic recombination rates in rice

Plant Biotechnology Journal, EarlyView.
Summary Crop breeding fundamentally depends on meiotic crossovers (COs) to reshuffle genetic material and integrate favourable alleles into elite cultivars. Recombination frequency is of paramount importance in this process. Higher recombination rates enhance the probability of breaking linkage drag and generating novel allelic combinations.
Yafei Li, Hanli You, Xinjie Cheng, Bingxin Wang, Yangzi Zhao, Jiawei Chen, Lei Cao, Minsi Wen, Yansong Zhang, Zhuoran Chen, Qiong Luo, Zhukuan Cheng   +11 more
wiley   +1 more source

Patronin mediates a switch from kinesin-13–dependent poleward flux to anaphase B spindle elongation

Journal of Cell Biology, 2013
Patronin counteracts KLP10A activity at spindle poles to stabilize microtubule minus ends and induce spindle elongation during anaphase B.
Haifeng Wang, I. Brust-Mascher, G. Civelekoglu-Scholey, J. Scholey   +3 more
semanticscholar   +1 more source

An Australian chickpea pan‐genome provides insights into genome organization and offers opportunities for enhancing drought adaptation for crop improvement

Plant Biotechnology Journal, EarlyView.
Summary Chickpea (Cicer arietinum L.) is an important legume crop that has been subjected to intensive breeding, resulting in limited genetic diversity. Australia is the world's second largest producer and the leading exporter of chickpea; the genomic architecture of its cultivars remains largely unexplored.
Vanika Garg, Rutwik Barmukh, Yan Huang, Annapurna Chitikineni, Kristy Hobson, Bicheng Yang, Yong Jia, Shengnan Bi, Sukhjiwan Kaur, Muhammad Ahsan Asif, Matthew Hayden, Sally Norton, Darshan L. Sharma, Kadambot H. M. Siddique, Xin Liu, Chengdao Li, Rajeev K. Varshney   +16 more
wiley   +1 more source

PI 3-kinase-dependent phosphorylation of Plk1–Ser99 promotes association with 14-3-3γ and is required for metaphase–anaphase transition

Nature Communications, 2013
Polo-like kinase 1 (Plk1) controls multiple aspects of mitosis and is activated through its phosphorylation at Thr210. Here we identify Ser99 on Plk1 as a novel mitosis-specific phosphorylation site, which operates independently of Plk1–Thr210 ...
Kousuke Kasahara, H. Goto, I. Izawa, T. Kiyono, N. Watanabe, S. Elowe, E. Nigg, M. Inagaki   +7 more
semanticscholar   +1 more source

Optimised Ribosome Profiling Reveals New Insights Into Translational Regulation in Synchronised Chlamydomonas reinhardtii Cultures

Plant, Cell &Environment, EarlyView.
ABSTRACT Deep sequencing of ribosome footprints, also known as ribosome profiling (Ribo‐seq), enables the quantification of mRNA translation and a comprehensive view of the translatome landscape. Here, we report an optimised Ribo‐seq protocol and analysis pipeline for the model green alga, Chlamydomonas reinhardtiii (Chlamydomonas).
Yen‐Ling Lin, Eva Yuhua Kuo, Shih‐Yi Wang, Chih‐Chi Lee, Su‐Chiung Fang   +4 more
wiley   +1 more source

PLK4 is a potential therapeutic target in nonmelanoma skin cancers: Evidence from molecular and in vivo studies

Photochemistry and Photobiology, EarlyView.
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye, Debra R. Garvey, Gagan Chhabra, Chandra K. Singh, Minakshi Nihal, Nihal Ahmad   +5 more
wiley   +1 more source

Aberrant meiotic behavior in Agave tequilana Weber var. azul

BMC Plant Biology, 2002
Background Agave tequilana Weber var. azul, is the only one variety permitted by federal law in México to be used for tequila production which is the most popular contemporary alcoholic beverage made from agave and recognized worldwide.
Rodríguez-Garay Benjamin, Ruvalcaba-Ruiz Domingo   +1 more
doaj   +1 more source