Results 111 to 120 of about 52,438 (267)
Journal of Cell Biology, 1995 During mitosis in Ptk1 cells anaphase is not initiated until, on average, 23 +/- 1 min after the last monooriented chromosome acquires a bipolar attachment to the spindle--an event that may require 3 h (Rieder, C. L., A. Schultz, R. W.
C. Rieder +3 more
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Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells
Journal of Applied Toxicology, Volume 45, Issue 8, Page 1555-1571, August 2025.ABSTRACT Human mesenchymal stem/stromal cells (hMSCs) can differentiate into mesoderm‐type cells, making them suitable candidates for tissue repair therapies. However, their relatively low frequency in adult tissue necessitates ex vivo expansion prior to regenerative medicine applications, and therefore, long‐term hMSC genetic stability during ...
Marc A. Beal +11 more
wiley +1 more source
ACTION SPECTRA FOR MITOTIC SPINDLE DESTRUCTION AND ANAPHASE DELAY FOLLOWING IRRADIATION OF THE CYTOPLASM WITH AN ULTRAVIOLET MICROBEAM* [PDF]
, 1967 Darrell Q. Brown, Raymond E. Zirkle
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Molecular Ecology Resources, Volume 25, Issue 6, August 2025.ABSTRACT Genomic incompatibilities and differential ecological adaptation are thought to be fundamental mechanisms of speciation. In this study, we generated a chromosome‐scale reference genome and annotation for Gopherus morafkai , the Sonoran Desert tortoise, and conducted a detailed analysis of genes under positive selection with its sister species,
Sarah M. Baty +6 more
wiley +1 more source
THE BEHAVIOR OF STRONG AND WEAK CENTROMERES AT SECOND ANAPHASE OF DROSOPHILA MELANOGASTER [PDF]
, 1960 Mark Ptashne
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Advanced Science, Volume 12, Issue 25, July 3, 2025.During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li +15 more
wiley +1 more source
Are dicentric anaphase bridges formed by somatic recombination in X chromosome inversion heterozygotes of Drosophila melanogaster? [PDF]
, 1972 J. R. Merriam +2 more
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Genes & Development, 1998 The spindle assembly checkpoint mechanism delays anaphase initiation until all chromosomes are aligned at the metaphase plate. Activation of the anaphase-promoting complex (APC) by binding of CDC20 and CDH1 is required for exit from mitosis, and APC has ...
G. Fang +3 more
semanticscholar +1 more source
Microscopy Research and Technique, Volume 88, Issue 7, Page 2048-2062, July 2025.ABSTRACT Haloxyfop‐R‐methyl (HRM) is extensively employed to control annual and perennial grass weeds. This study aimed to investigate the cyto‐genotoxic effects of HRM at concentrations of 1.19, 2.38, and 4.76 mg/L over various time intervals (24, 48, 72, and 96 h) on Allium cepa root.
Recep Liman +4 more
wiley +1 more source
A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase. [PDF]
, 1988 Tatsuya Hirano +2 more
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