Results 121 to 130 of about 66,778 (245)
Approaches to repurposing reverse transcriptase antivirals in cancer
British Journal of Clinical Pharmacology, Volume 91, Issue 9, Page 2494-2506, September 2025.This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head +2 more
wiley +1 more source
Avian Lifespan Network Reveals Shared Mechanisms and New Key Players in Animal Longevity
Aging Cell, Volume 24, Issue 9, September 2025.In this work, we found that birds with similar lifespans exhibit convergent evolution in specific genes, suggesting that shared evolutionary pressures shape the genetic basis of lifespan similarity across species. By investigating protein–protein interactions across genes evolving convergently in long‐ and short‐lived species, we identified a network ...
Mirko Martini +3 more
wiley +1 more source
Saccharomyces cerevisiae cdcl5 Mutants Arrested at a Late Stage in Anaphase Are Rescued by Xenopus cDNAs Encoding N-ras or a Protein with β-Transducin Repeats [PDF]
, 1993 openalex +1 more source
Cancer Science, Volume 116, Issue 9, Page 2444-2456, September 2025.Bioinformatic analysis of 42 KLHL family genes identified KLHL5 as a potential prognostic biomarker for colorectal cancer (CRC), with higher expression in the common molecular subtype (CMS) 4 CRC, which is characterized by poorer overall and recurrence‐free survival rates compared to other CMS groups. KLHL5 immunohistochemical analysis was performed on
Kyosuke Habu +15 more
wiley +1 more source
A QUANTITATIVE STUDY OF ANAPHASE MOVEMENT IN THE APHID TAMALIA
, 1943 Hans Ris
openalex +2 more sources
Journal of Oral Pathology &Medicine, Volume 54, Issue 8, Page 706-714, September 2025.ABSTRACT Background The incidence of squamous cell carcinoma of the oral tongue (SCCOT) among young adults is increasing in several regions of the world. Age‐dependent differences in the biology of SCCOT have been suspected. Methods We used the Olink Explore 3072 high‐throughput platform to comprehensively quantify plasma proteins in 24 young (≤ 40 ...
Xiaolian Gu +8 more
wiley +1 more source
Phytochrome A is required for light‐inhibited germination of Aethionema arabicum seed
New Phytologist, Volume 247, Issue 5, Page 2134-2146, September 2025.Summary The germination of most seeds is influenced by the duration, intensity, and quality of light. The seeds of the model plant Arabidopsis are positive photoblastic and require light to germinate. The germination of negative photoblastic seeds is inhibited by white light.
Zsuzsanna Mérai +4 more
wiley +1 more source
Regulation of anaphase in mammalian meiosis
, 2012 Missegregation of chromosomes during meiosis leads to formation of aneuploid eggs. Estimates suggest that in humans, about 10-30% of fertilised eggs and one-third of all miscarriages are aneuploid. Accurate chromosome segregation depends on the coordination between stepwise cohesion resolution and attachments of homologous chromosomes through ...
openaire +2 more sources
CDK1 Inactivation Regulates Anaphase Spindle Dynamics and Cytokinesis In Vivo [PDF]
, 1997 Sally P. Wheatley +5 more
openalex +1 more source
Dynamic patterns of repeats and retrotransposons in the centromeres of Humulus lupulus L.
New Phytologist, Volume 247, Issue 6, Page 2766-2780, September 2025.Summary The centromere has a conserved function across eukaryotes; however, the associated DNA sequences exhibit remarkable diversity in both size and structure. In plants, some species possess well‐defined centromeres dominated by tandem satellite repeats and centromeric retrotransposons, while others have centromeric regions composed almost entirely ...
Lucie Horáková +13 more
wiley +1 more source