Results 121 to 130 of about 154,428 (289)

Ecotoxicological Evaluation of Organic Sunscreens Used Worldwide, Alone and in Mixture, on Terrestrial Plants

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The environmental hazards of sunscreens are discussed worldwide. However, there are few ecotoxicological studies on these compounds alone for edaphic organisms, and none for their mixtures. Avobenzone (1 and 10 ng/L), octocrylene (10 and 100 μg/L), and oxybenzone (2 and 20 μg/L), alone and in binary combinations (between the lowest and the ...
Diego Espirito Santo   +6 more
wiley   +1 more source

Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis.

open access: yesPLoS Genetics, 2020
In mitosis and meiosis, chromosome segregation is triggered by the Anaphase-Promoting Complex/Cyclosome (APC/C), a multi-subunit ubiquitin ligase that targets proteins for degradation, leading to the separation of chromatids.
Damien Garrido   +5 more
doaj   +1 more source

Bulbil formation in stress: Crucial role of triploid fitness in mixed ploidy dynamics in Costus speciosus

open access: yesPlant Species Biology, EarlyView.
Upon prolonged waterlogging, a Costus speciosus plant developed bulbils at stem node. Karyotype analysis, nucleolar staining, and anatomical study revealed its triploid status and developmental aspects. Prevalence of tetraploid, abundance, and unique reproductive fecundity of the triploid, indicates its determinant role in coexistence of the multiple ...
Surochita Basu   +3 more
wiley   +1 more source

Pregnancy and perinatal outcomes after day 5 versus day 6 blastocyst‐stage embryo transfer: A systematic review and meta‐analysis

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
We conducted a meta‐analysis to compare the pregnancy and perinatal outcomes after day 5 versus day 6 single frozen‐thawed blastocyst transfer, aims to identify more appropriate strategies for transplantation. ART practitioners should give priority to transfer D5 rather than D6 blastocysts in single vitrified‐warmed cycle in clinical practice. Abstract
Wenhui Hou   +6 more
wiley   +1 more source

In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells. [PDF]

open access: yes, 1990
To investigate the mechanisms of spindle elongation and chromosome separation in the fission yeast Schizosaccharomyces pombe, we have developed an in vitro assay using a temperature-sensitive mutant strain, nuc2.
Cande, WZ   +3 more
core  

YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice

open access: yesCell Proliferation, EarlyView.
Specifically ablating Ykt6 in pre‐meiotic germ cells and meiotic spermatocytes leads to complete sterility and meiotic arrest in conditional knockout male mice. YTK6 is required for stabilising intercellular bridges between spermatocytes due to its key role in maintaining protein homeostasis and vesicular transport‐dependent functions in spermatocytes,
Jie Cen   +8 more
wiley   +1 more source

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

open access: yesCell Proliferation, EarlyView.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao   +7 more
wiley   +1 more source

Fin1-PP1 Helps Clear Spindle Assembly Checkpoint Protein Bub1 from Kinetochores in Anaphase

open access: yesCell Reports, 2016
Summary: The spindle assembly checkpoint (SAC) monitors chromosome attachment defects, and the assembly of SAC proteins at kinetochores is essential for its activation, but the SAC disassembly process remains unknown.
Michael Bokros   +4 more
doaj   +1 more source

Development of NAFLD‐Specific Human Liver Organoid Models on a Microengineered Array Chip for Semaglutide Efficacy Evaluation

open access: yesCell Proliferation, EarlyView.
Microporous array organ chips were integrated with commercially available well plates to develop organoid chip platforms, which enable modelling of hepatic physiology and non‐alcoholic fatty liver disease (NAFLD) pathogenesis, as well as evaluation of semaglutide therapeutics. ABSTRACT Progressive non‐alcoholic fatty liver disease (NAFLD) may culminate
Xiao‐yan You   +3 more
wiley   +1 more source

Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells [PDF]

open access: gold, 2023
Rajendra Bhati   +9 more
openalex   +1 more source

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