On the Anaphase Movement of Chromosomes [PDF]
M M, Rhoades, H, Vilkomerson
openaire +2 more sources
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye +5 more
wiley +1 more source
The distribution of cytoplasmic microtubules throughout the cell cycle of the centric diatom Stephanopyxis turris: their role in nuclear migration and positioning the mitotic spindle during cytokinesis. [PDF]
The cell cycle of the marine centric diatom Stephanopyxis turris consists of a series of spatially and temporally well-ordered events. We have used immunofluorescence microscopy to examine the role of cytoplasmic microtubules in these events.
Cande, WZ, McDonald, KL, Wordeman, L
core
Sex differences in the physiological response to acute anterior cruciate ligament overuse
Abstract figure legend With equivalent in vivo fatigue loading of the anterior cruciate ligament (ACL), females accumulate more tissue damage and mount a slower reparative response than males, when the applied loads between sexes are equivalent. By contrast, males accumulate less tissue damage and mount a robust reparative response that includes ...
Stephen H. Schlecht +5 more
wiley +1 more source
RCS1, a substrate of APC/C, controls the metaphase to anaphase transition
Wei-meng Zhao +5 more
openalex +1 more source
CDK1 Inactivation Regulates Anaphase Spindle Dynamics and Cytokinesis In Vivo [PDF]
Sally P. Wheatley +5 more
openalex +1 more source
Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano +6 more
wiley +1 more source
SiR‐XActin: A Fluorescent Probe for Imaging Actin Dynamics in Live Cells
SiR‐XActin is a far‐red fluorescent probe for live‐cell imaging of actin that avoids genetic modification and minimizes disruption of actin dynamics, due to its lower binding affinity. Based on jasplakinolide‐like natural product hybrids and Si–Rhodamine, it offers photostable live‐cell no‐wash staining across cell types and microscopy techniques ...
Veselin Nasufovic +14 more
wiley +2 more sources
UBE2S drives elongation of K11-linked ubiquitin chains by the Anaphase-Promoting Complex
Tao Wu +5 more
openalex +1 more source
The Double Face of Base Excision Repair: Preventing and Triggering Double‐Strand Breaks
Base excision repair is conserved from bacteria to man, robustly eliminating oxidized bases in DNA and reinserting the appropriate nucleotide to restore an intact double helix. Recent results describe conditions and mechanisms that misregulate long‐patch BER to generate double‐strand breaks, triggering chromosome fragmentation and cell death, altering ...
Susan M. Gasser
wiley +1 more source

