Results 271 to 280 of about 170,053 (305)

Rephrasing anaphase: separase FEARs shugoshin

Chromosoma, 2005
Cleavage of the ring-like cohesin complex by separase triggers segregation of sister chromatids in anaphase. This simplistic model has recently been extended by exciting discoveries on three levels: regulation of anaphase by posttranslational modifications and the cohesin protector shugoshin; non-proteolytic roles of separase; and cohesin-independent ...
Stemmann, Olaf, Boos, Dominik, Gorr, Ingo H.   +2 more
openaire   +3 more sources

Nocodazole pretreatment in anaphase selectively reduces anaphase B in PtK1 cells

Cell Motility, 1983
AbstractDuring early anaphase PtK1 cells were briefly treated with the rapidly reversible microtubule (MT) poison nocodazole. This treatment abruptly stopped chromosome motion and effected a large decrease in spindle birefringence. On removal of the drug, chromosome to pole motion (anaphase A) returned, though at a lesser rate but not extent than ...
J A, Snyder, S I, Vogt, S L, McLelland
openaire   +2 more sources

Chromosome errors at mitotic anaphase

Genome, 1992
Errors in mitotic divisions were assayed using various satellite DNAs as probes, hybridized in situ, to show that they included nondisjunction, chromosome and chromatid lagging, chromatid malsegregation, and monopolar segregations. The total rates of error were 1.7, 1.1, and 0.6% for chromosomes X, 17, and 18, respectively. Lagging was the most common
J H, Ford, A T, Correll
openaire   +2 more sources

Lactate regulates cell cycle by remodelling the anaphase promoting complex

Nature, 2023
Weihai Liu, Yun Wang, L. Bozi, P. Fischer, Mark P. Jedrychowski, Haopeng Xiao, Tao Wu, Narek Darabedian, Xiadi He, E. Mills, Nils Burger, Sanghee Shin, Anita Reddy, Hans-Georg Sprenger, Nhien V. Tran, Sally Winther, S. Hinshaw, Jingnan Shen, H. Seo, Kijun Song, A. Xu, Luke Sebastian, Jean Zhao, S. Dhe-Paganon, Jianwei Che, S. Gygi, H. Arthanari, Edward T. Chouchani   +27 more
semanticscholar   +1 more source

The many phases of anaphase

Trends in Biochemical Sciences, 2005
Anaphase is the stage of the cell cycle in which duplicated chromosomes separate and move towards opposite poles of the cell. Although its chromosome movements have always been viewed as majestic, until recently anaphase lacked obvious landmarks of regulation.
Armand, de Gramont, Orna, Cohen-Fix
openaire   +2 more sources

Nucleotide requirements for anaphase chromosome movements in permeabilized mitotic cells: Anaphase B but not anaphase a requires ATP

Cell, 1982
Permeabilized PtK1 cells continue to undergo anaphase chromosome movements provided MgATP is included in the lysis medium. However, chromosome-to-pole movement (anaphase A) and spindle elongation (anaphase B) differ with respect to nucleotide requirements.
openaire   +2 more sources

The mechanism of anaphase spindle elongation

BioEssays, 1989
AbstractAt anaphase chromosomes move to the spindle poles (anaphase A) and the spindle poles move apart (anaphase B). In vitro studies using isolated diatom spindles demonstrate that the primary mechano‐chemical event responsible for spindle elongation is the sliding apart of half‐spindle microtubules.
W Z, Cande, C J, Hogan
openaire   +2 more sources

The anaphase promoting complex/cyclosome: a machine designed to destroy

Nature reviews. Molecular cell biology, 2006
J. Peters
semanticscholar   +1 more source

C-anaphases rediscovered

Human Genetics, 1988
Y. Chamla, K. Madan
openaire   +2 more sources

The anaphase promoting complex.

Cancer surveys, 1997
We have proposed a preliminary model of how the anaphase promoting complex functions throughout the cell cycle, but despite the flurry of recent publications characterizing the APC--its components, regulation and substrate specificity--many fundamental questions remain to be answered.
A M, Page, P, Hieter
openaire   +1 more source