Results 151 to 160 of about 138,544 (375)

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

open access: yesAllergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy   +17 more
wiley   +1 more source

Anaphylaxis - a 2020 Practice Parameter Update, Systematic Review and GRADE Analysis.

open access: yesJournal of Allergy and Clinical Immunology, 2020
M. Shaker   +48 more
semanticscholar   +1 more source

Non‐Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First‐In‐Class IgE Antibody Recognising Folate Receptor Alpha

open access: yesAllergy, EarlyView.
MOv18 IgE, the first‐in‐class IgE antibody targeting the cancer antigen folate receptor alpha (FR⍺) showed early signs of efficacy and was well tolerated in a first‐in‐human clinical trial, with transient urticarial skin reactions as the most common toxicity.
Chara Stavraka   +28 more
wiley   +1 more source

Pilot Study: Program Evaluation of Peanut Oral Immunotherapy in a Private Clinic [PDF]

open access: yes, 2019
The privilege of providing a therapy perceived by patients and families as “life changing” has seasoned physicians describing food oral immunotherapy (OIT) as one of “the most impactful and rewarding thing that they have done in medicine” (Wasserman ...
Olson, Kinga
core   +1 more source

Current use of push‐dose epinephrine: Survey and interview results from academic clinicians in emergency medicine

open access: yes
Academic Emergency Medicine, EarlyView.
Andrew K. Posen   +3 more
wiley   +1 more source

A multicenter anaphylaxis registry in Korea: Clinical characteristics and acute treatment details from infants to older adults

open access: yesWorld Allergy Organization Journal, 2020
Background: Although the prevalence of anaphylaxis is increasing worldwide, the large-scale studies in Asia evaluating anaphylaxis in all age groups are limited.
Kyunguk Jeong   +29 more
doaj  

Fish Allergenicity Ladder and Parvalbumin Epitopes for Predicting Clinical Cross‐Reactivity and Reintroduction in Chinese Population

open access: yesAllergy, EarlyView.
Clinical history including self‐reported history and oral food challenge outcome, and sIgE sensitization profile of 200 subjects with suspected fish allergy was analyzed to construct a 3‐step fish allergenicity ladder. The allergenicity ladder was positively linked to the relative parvalbumin content of fish muscle but not to differences in the IgE ...
Christine Y. Y. Wai   +21 more
wiley   +1 more source

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