Results 151 to 160 of about 138,544 (375)
Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622
Allergy, EarlyView.SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.Michael B. Murphy, Laura Vitale, Thomas O'Neill, Deena M. Maurer, Linda Malenchek, Andrea Crocker, Colleen Patterson, Laura Mills‐Chen, Virginia Saley, Nicole M. Antczak, James M. Boyer, Kelly M. McManus, Noe Rico Montanari, Russell A. Hammond, Joel Goldstein, Lawrence J. Thomas, Tibor Keler, Diego Alvarado +17 morewiley +1 more sourceAnaphylaxis - a 2020 Practice Parameter Update, Systematic Review and GRADE Analysis.
Journal of Allergy and Clinical Immunology, 2020 M. Shaker, D. Wallace, D. Golden, J. Oppenheimer, J. Bernstein, R. Campbell, C. Dinakar, A. Ellis, M. Greenhawt, D. Khan, D. Lang, E. Lang, J. Lieberman, J. Portnoy, M. Rank, D. Stukus, Julie Wang, N. Riblet, A. Bobrownicki, Teresa Bontrager, Jarrod Dusin, Jennifer Foley, B. Frederick, Eyitemi Fregene, Sage T. Hellerstedt, F. Hassan, Kori Hess, C. Horner, Kelly Huntington, Poojita Kasireddy, D. Keeler, Bertha Kim, P. Lieberman, E. Lindhorst, F. McEnany, Jennifer Milbank, Helen Murphy, Oriana Pando, Ami K. Patel, N. Ratliff, R. Rhodes, Kim Robertson, Hope Scott, Audrey Snell, Rhonda Sullivan, Varahi Trivedi, Azadeh Wickham, Workgroup Contributors, Joint Task Force on Practice Parameters Reviewers +48 moresemanticscholar +1 more sourceNon‐Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First‐In‐Class IgE Antibody Recognising Folate Receptor Alpha
Allergy, EarlyView.MOv18 IgE, the first‐in‐class IgE antibody targeting the cancer antigen folate receptor alpha (FR⍺) showed early signs of efficacy and was well tolerated in a first‐in‐human clinical trial, with transient urticarial skin reactions as the most common toxicity.Chara Stavraka, Jitesh Chauhan, Silvia Crescioli, Sheila M. McSweeney, Amy Pope, Cheryl Gillett, Ashley Di Meo, Ioannis Prassas, Roman Laddach, Katie Stoker, Alexandra J. McCraw, Rebecca Adams, Thomas J. Tull, Nabeel Naban, Zena Willsmore, Kristina V. Semkova, Clive E. H. Grattan, John McGrath, Stephen J. Till, Christopher J. Corrigan, Rebecca Kristeleit, Sophia Tsoka, Eleftherios P. Diamandis, Katie E. Lacy, Sarah Pinder, Debra H. Josephs, James Spicer, Heather J. Bax, Sophia N. Karagiannis +28 morewiley +1 more sourceA multicenter anaphylaxis registry in Korea: Clinical characteristics and acute treatment details from infants to older adults
World Allergy Organization Journal, 2020 Background: Although the prevalence of anaphylaxis is increasing worldwide, the large-scale studies in Asia evaluating anaphylaxis in all age groups are limited.Kyunguk Jeong, Young-Min Ye, Sang-Ha Kim, Kyung Won Kim, Jeong Hee Kim, Ji-Won Kwon, Song-I. Yang, So-Yeon Lee, Eun Hee Chung, Mi-Ae Kim, Yoon Hee Kim, Hye-Young Kim, Gwang Cheon Jang, Joo-Hee Kim, Eunjoo Lee, Jihyun Kim, Kangmo Ahn, Yoon-Seok Chang, Gyu-Young Hur, Jeongmin Lee, Taek Ki Min, Bok-Yang Pyun, Kyung Hee Park, Jaechun Lee, Tae Won Song, Hye Mi Jee, Yoo Seob Shin, Dankyu Yoon, Jeom-Kyu Lee, Sooyoung Lee +29 moredoaj Fish Allergenicity Ladder and Parvalbumin Epitopes for Predicting Clinical Cross‐Reactivity and Reintroduction in Chinese Population
Allergy, EarlyView.Clinical history including self‐reported history and oral food challenge outcome, and sIgE sensitization profile of 200 subjects with suspected fish allergy was analyzed to construct a 3‐step fish allergenicity ladder. The allergenicity ladder was positively linked to the relative parvalbumin content of fish muscle but not to differences in the IgE ...Christine Y. Y. Wai, Nicki Y. H. Leung, Agnes S. Y. Leung, Man Fung Tang, Åsa Marknell DeWitt, Jaime S. Rosa Duque, Gilbert T. Chua, Yat Sun Yau, Wai Hung Chan, Po Ki Ho, Mike Y. W. Kwan, Qun Ui Lee, Joshua S. C. Wong, Ivan C. S. Lam, James W. C. H. Cheng, David C. K. Luk, Zhongyi Liu, Noelle Anne Ngai, Oi Man Chan, Patrick S. C. Leung, Gary W. K. Wong, Ting Fan Leung +21 morewiley +1 more source