Results 61 to 70 of about 60,111 (283)

Knowledge and experience of radiologists working in Istanbul on radiographic contrast medium anaphylaxis

AIMS Allergy and Immunology, 2017
Radiologists are among the physicians with the highest probability of encountering cases with anaphylaxis. Therefore, they should be familiar with the recent developments in the diagnosis and treatment of anaphylaxis.
Gozde Arslan, Ayla Balci, Rahmi Cubuk, Feyzullah Cetinkaya   +3 more
doaj   +1 more source

Anaphylaxis in children [PDF]

Pediatric Allergy and Immunology, 2020
AbstractAnaphylaxis in children is a potential acute life‐threatening systemic hypersensitivity reaction. Anaphylaxis fatality rate is estimated to be 0.65% to 2%. Food is the main anaphylaxis trigger in children, notably cow's milk, peanuts, and tree nuts. Mucocutaneous manifestations are observed in more than 90% of cases, but it is not essential for
Tanno, Luciana Kase, Demoly, Pascal
openaire   +5 more sources

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source

Investigation of poor predictive factors in extensive stage small cell lung cancer under etoposide‐platinum‐atezolizumab treatment

Thoracic Cancer, Volume 13, Issue 23, Page 3384-3392, December 2022., 2022
In ES‐SCLC under etoposide‐platinum‐atezolizumab, 6‐month survival was 68.6%. In survival analysis for OS, lactate dehydrogenase (LDH), c‐reactive protein (CRP), and forced vital capacity (%) were significant factors. In multivariate analysis for PFS, sex, and LDH were significant. Abstract Background The phase III trial IMpower133 showed that platinum
Jeong Uk Lim, Hye Seon Kang, Ah. Young Shin, Chang Dong Yeo, Sung Kyoung Kim, Jin Woo Kim, Seung Joon Kim, Sang Haak Lee   +7 more
wiley   +1 more source

Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, Accepted Article.
Objectives Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The Phase III MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E Wechsler, Jared Silver, Gerhard Wolff, Robert G Price, Rejina Verghis, Peter F Weller, Peter A Merkel, Paneez Khoury, on behalf of the EGPA Mepolizumab Open‐Label Extension study group, Arnaud Bourdin, Pascal Chanez, Anoop Chauhan, Vincent Cottin, Gerald Gleich, Berhnard Hellmich, Tomonori Ishii, David Jayne, Jean‐Emmanuel Kahn, Peter Kern, Nader Khalidi, Ina Koetter, Carol Langford, Amy Markezich, Paul Monach, Shamsa Naveed, Peter Oelzner, Kenneth Pinna, Xavier Puechal, Emory H Robinette, Florence Roufosse, Reinhard Voll, Andrew Schafer, Kaharu Sumino, Masami Taniguchi, Phillip Lieberman   +34 more
wiley   +1 more source

Adverse events associated with monoclonal antibodies used for treatment of COVID‐19: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims This review aimed to synthesise the evidence related to the incidence of serious and non‐serious adverse events with the use of monoclonal antibodies (mAbs) among COVID‐19 patients. Methods Databases were searched from January 2020 to September 2023 for randomized clinical trials (RCTs) that used mAbs for the treatment of COVID‐19 regardless of ...
Htet Htet, Han You Kyung, Ismail Abdul Sattar Burud, Heethal Jaiprakash, Thiruselvi Subramaniam, Igor Iezhitsa, Renu Agarwal   +6 more
wiley   +1 more source

Safety of sulfamethoxazole–trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta‐analysis with active comparator disproportionality analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra, Lujain Ez Eddin, Fatemeh Ahmadi, Atefeh Jafari, Flory T. Muanda   +4 more
wiley   +1 more source

Fighting Antibiotic Resistance: Insights Into Human Barriers and New Opportunities

BioEssays, EarlyView.
Antibiotic resistance is a public health issue leading to the emergence of multi‐resistant bacteria. Human‐dependent factors are now driving the increase of resistance, notably through antibiotic misuse in human and animal health and environmental pollution.
Aubin Pitiot, Camille Rolin, Carole Seguin‐Devaux, Jacques Zimmer   +3 more
wiley   +1 more source

From Allergy to Angina: A Unique Presentation of Kounis Syndrome

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Kounis syndrome (KS) is a rare condition characterized by acute coronary syndrome (ACS) triggered by an allergic reaction. This report presents a case of high‐risk ACS associated with a food allergy. A 53‐year‐old male with no prior medical history presented to the emergency department with itching, facial swelling, chest tightness, shortness ...
Momen Ali, Ayman Helal, Mohammad El‐Din, Ibrahim Antoun   +3 more
wiley   +1 more source

Conformational Profile of Galactose‐α‐1,3‐Galactose (α‐Gal) and Structural Basis of Its Immunological Response

Chemistry – A European Journal, EarlyView.
A multilevel computational analysis of the disaccharide α‐Gal describes in detail its rigid conformational profile in solution, while multiscale hybrid (QM/MM) calculations, energy decomposition and analysis of non‐covalent interactions are used to probe the atomistic details of the binding of the disaccharide to the M86 antibody.
Golokesh Santra, Dimitrios A. Pantazis
wiley   +1 more source