Clinical significance of anaplasia in childhood rhabdomyosarcoma
Background: The presence of anaplastic features has been known to correlate with poor clinical outcome in various pediatric malignancies, including Wilms tumor and medulloblastoma but not in rhabdomyosarcoma.
Rania Labib +2 more
exaly +5 more sources
Gene expression study in retinoblastoma patients with different anaplasias and lateralities [PDF]
To investigate the differences in gene expression and functional enrichment associated with anaplasia and laterality in retinoblastoma patients. Two datasets were selected from the GEO database of the National Center for Biotechnology Information of the ...
Wan Li, Kangkang Xu, Fei Chen
doaj +4 more sources
Anaplasia in childhood rhabdomyosarcoma: An under reported entity
Background: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Anaplasia is a rare phenomenon seen in childhood RMS. The most common histologic subtype was Embryonal followed by Alveolar and spindle subtype.
Manisha Ahuja +6 more
doaj +3 more sources
Purpose: Gain of chromosome 6p has been associated with poor ocular survival in retinoblastoma and histopathologic grading of anaplasia with increased risk of metastatic spread and death.
Gustav Stålhammar +2 more
exaly +3 more sources
Case Report: ALK-positive histiocytosis presenting as an adrenal mass: a diagnostic trap due to unusual morphology [PDF]
BackgroundThe differential diagnosis of an adrenal mass is critical for clinical management. We report a case that expanded the spectrum of a rare disease and present a novel diagnostic trap for both pathologists and clinicians.MethodsHistopathological ...
Wenjing Ma +4 more
doaj +2 more sources
Anaplasia in Wilms tumor: A critical review
Abstract Anaplasia in Wilms tumor is recognized as the most important prognostically unfavorable histological feature. It is subtyped as focal anaplastic Wilms tumor (FAWT) and diffuse anaplastic Wilms tumor (DAWT). Outcomes of patients with DAWT remain poor in patients with stage III and IV tumors.
Gordan Vujanic
exaly +3 more sources
High Expression of WT1 and Low Expression of p53 in Archived Blocks of Children with Wilms Tumor in South Western Uganda [PDF]
Brian Ssenkumba,1 Barnabas Atwiine,2,3 Yekosani Mitala,1 Janet Adongo,4 Samuel Olowo,4 Rita Nabulya,1 Amnia Diaz Anaya,1 Raymond Atwine1 1Department of Pathology, Mbarara University of Science and Technology, Mbarara, Uganda; 2Department of Paediatrics ...
Ssenkumba B +7 more
doaj +2 more sources
A Case Report of Anaplastic Variant Juvenile Granulosa Cell Tumour [PDF]
Introduction: Anaplastic variant of juvenile granulosa cell tumor is one of the rarest ovarian malignancies. The aim of this study is to describe a case of anaplastic variant ovarian granulosa cell tumor in a 14-year-old girl with presentation of ...
Masoumeh Gharib +3 more
doaj +1 more source
Role of expression of p53 and Ki67 in the progression of Wilms tumor: Correlation with patients’ survival [PDF]
Background: Wilms tumor (WT) is the most frequent renal tumor of childhood and is a highly responsive tumor to chemotherapy. P53 and ki67 are two of the most important markers that have been evaluated in many cancers.
Ahmad Darwish, Doaa Alemam, Heba Sheta
doaj +1 more source
Anaplastic rhabdomyosarcoma of upper lip in a 3-year-old girl
Rhabdomyosarcoma is an aggressive malignant striated muscle neoplasm commonly seen in children involving orbit, paranasal sinuses, cheek, tongue, and rarely upper lip. The anaplastic subtype is further rare and associated with poor prognosis.
Arti Khatri +3 more
doaj +1 more source

