Synthesis of Anabaenopeptins With a Strategic Eye Toward N-Terminal Sequence Diversity. [PDF]
Venneti NM +7 more
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Anti-Idiotypic Antibodies in Immune Regulation and Disease: Therapeutic Promise for Next-Generation Vaccines. [PDF]
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Transdisciplinary approaches for the study of cyanobacteria and cyanotoxins. [PDF]
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Hydroculture Cultivation of Strawberries as Potential Reference Material for Microcystin Analysis: Approaches and Pitfalls. [PDF]
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Systematic Review on CyanoHABs in Central Asia and Post-Soviet Countries (2010-2024). [PDF]
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Anatoxin-a, homoanatoxin-a, and dihydroanatoxin-a are potent cyanobacterial neurotoxins. They are biosynthesized in cyanobacteria from proline and acetate by a pathway involving three polyketide synthases. We report the identification of carboxy-anatoxin-a, carboxy-homoanatoxin-a, and carboxy-dihydroanatoxin-a in acidic extracts of Cuspidothrix ...
Andreja Kust +2 more
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Biosynthesis of anatoxin-a and analogues (anatoxins) in cyanobacteria
Toxicon, 2014Freshwater cyanobacteria produce secondary metabolites that are toxic to humans and animals, the so-called cyanotoxins. Among them, anatoxin-a and homoanatoxin-a are potent neurotoxins that are agonists of the nicotinic acetylcholine receptor. These alkaloids provoke a rapid death if ingested at low doses. Recently, the cluster of genes responsible for
Annick, Méjean +3 more
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Anatoxin-a (AN) and homoanatoxin (HMAN) are two powerful nicotinic agonists. Symptoms of AN and HMAN toxicosis include tremors, convulsions, muscle fasciculations, and rapid death due to respiratory failure. AN is unstable under natural conditions and is naturally degraded either partially or totally to the nontoxic products dihydroanatoxin-a and ...
Justine Dauphard +4 more
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Analysis of Anatoxin-a by GCIECD*
Journal of Analytical Toxicology, 1988Anatoxin-a (ANTX-a), a potent cholinergic alkaloid produced by some toxigenic strains of the cyanobacterium Anabaena flos-aquae, has been responsible for death of livestock, pets, and wildlife. An increase in the frequency of cyanobacterial blooms in fresh waters of temperate North America has produced a concomitant increase in the threat posed by ...
D K, Stevens, R I, Krieger
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