Results 191 to 200 of about 23,269,289 (245)
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Science of the Total Environment, 2020
Toxic cyanobacteria are a concern worldwide because they can adversely affect humans, animals, and ecosystems. However, neurotoxins produced by freshwater cyanobacteria are understudied relative to microcystin. Thus, the objective of this critical review
V. G. Christensen, Eakalak Khan
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Toxic cyanobacteria are a concern worldwide because they can adversely affect humans, animals, and ecosystems. However, neurotoxins produced by freshwater cyanobacteria are understudied relative to microcystin. Thus, the objective of this critical review
V. G. Christensen, Eakalak Khan
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Mass Spectrometric Analysis of Anatoxin-a
Journal of Analytical Toxicology, 1989Secondary ion mass spectrometry (SIMS), gas chromatography/mass spectrometry (GC/MS), desorption chemical ionization/mass spectrometry (DCI/MS), and thermospray/mass spectrometry (TSP/MS) were evaluated for the detection of a low-molecular weight biological toxin, anatoxin-a.
M M, Ross, D A, Kidwell, J H, Callahan
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Analysis of Anatoxin-a by GCIECD*
Journal of Analytical Toxicology, 1988Anatoxin-a (ANTX-a), a potent cholinergic alkaloid produced by some toxigenic strains of the cyanobacterium Anabaena flos-aquae, has been responsible for death of livestock, pets, and wildlife. An increase in the frequency of cyanobacterial blooms in fresh waters of temperate North America has produced a concomitant increase in the threat posed by ...
D K, Stevens, R I, Krieger
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Revista Intertox de Toxicologia, Risco Ambiental e Sociedade, 2015
Current natural conditions as well as human activities have been promoting changes and increasing stress in the freshwater and marine environment. One of the consequences is the worldwide occurrence of cyanobacterial (blue-green algae) blooms, which is considered a serious environmental and economic problem (ARAOZ, et al 2005).
Vania Rodríguez, Ernani Pinto
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Current natural conditions as well as human activities have been promoting changes and increasing stress in the freshwater and marine environment. One of the consequences is the worldwide occurrence of cyanobacterial (blue-green algae) blooms, which is considered a serious environmental and economic problem (ARAOZ, et al 2005).
Vania Rodríguez, Ernani Pinto
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Harmful Algae, 2021
Water bloom-forming cyanobacteria have a severe impact on freshwater quality. Although some cyanobacterial toxins such as microcystins have been studied extensively, other toxins like anatoxin-a (ATX) and their structural analogs - as well as ...
L. Blahová +8 more
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Water bloom-forming cyanobacteria have a severe impact on freshwater quality. Although some cyanobacterial toxins such as microcystins have been studied extensively, other toxins like anatoxin-a (ATX) and their structural analogs - as well as ...
L. Blahová +8 more
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The detection of airborne anatoxin-a (ATX) on glass fiber filters during a harmful algal bloom
, 2021Sutherland JW, Turcotte RJ, Molden E, Moriarty V, Kelly M, Aubel M, Foss A. 2021. The detection of airborne anatoxin-a (ATX) on glass fiber filters during a harmful algal bloom. Lake Reserv Manage. 37:113–119.
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Dispersive magnetic immunoaffinity extraction. Anatoxin-a determination
Journal of Chromatography A, 2017Specific monoclonal antibodies were coupled with magnetic Sepharose-based beads and used, for the first time. The methodology was applied to preconcentrate anatoxin-a from water and the later determination by ion mobility spectrometry (IMS). Dispersive magnetic immunoaffinity (d-MagIA) extraction methodology provided a limit of detection of 0.02μgL-1 ...
Tinh, Le +6 more
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Homoanatoxin: A potent analogue of anatoxin-a
Biochemical Pharmacology, 1992The natural toxin anatoxin-a (AnTx) is a potent nicotinic agonist that is valuable for the study of nicotinic receptors. We have synthesized 2-(propan-1-oxo-1-yl)-9-azabicyclo[4.2.1]non-2-ene, the homologue of AnTx in which the side-chain is extended by one methylene unit from a methyl to an ethyl ketone.
Wonnacott, S +5 more
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Conformational studies on (+)-anatoxin-a and derivatives
Journal of Computer-Aided Molecular Design, 1992Anatoxin-a (AnTX) is a highly potent agonist acting at the nicotinic acetylcholine receptor (nAChR) and represents a valuable tool in the study of this receptor. Molecular mechanics, semi-empirical and ab initio molecular orbital energy minimization procedures were conducted to investigate the conformation of AnTX.
P E, Thompson +3 more
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Neurotoxic alkaloids: synthesis of (±)-anatoxin-a
J. Chem. Soc., Chem. Commun., 1987Synthese a partir de tosylamino-2 heptadiene-5,6oate d'ethyle via l'ester d'ethyle de la tosyl-1 vinyl-5 proline et la tosyl-9 aza-9 bicyclo [4.2.1] nonanone ...
Peter Vernon, Timothy Gallagher
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