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Classification of ANCA-Associated Vasculitis

Current Rheumatology Reports, 2013
Classification of the ANCA-associated vasculitides remains controversial. Existing systems, developed by the American College of Rheumatology (ACR) in 1990, the Chapel Hill Consensus Conference (CHCC) in 1994 and updated in 2012, and the European Medicines Agency algorithm, all have deficiencies, especially when applied to unselected patients.
Irfan, Khan, Richard A, Watts
openaire   +2 more sources

Pathophysiology of ANCA-associated Vasculitis

Advances in Anatomic Pathology, 2017
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is characterized as inflammation of small-sized to medium-sized blood vessels and encompasses several clinicopathologic entities including granulomatosis with polyangiitis, microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis, and renal-limited ANCA-associated ...
Turki, Al-Hussain   +4 more
openaire   +2 more sources

ANCA-Associated Vasculitis

2009
The majority of patients with Wegener's granulomatosis (WG) or microscopic polyangiitis (MPA) have antineu-trophil cytoplasmic antibodies (ANCA) in their serum. This is particularly true of patients with "disseminated" disease, the great majority of whom are ANCA positive.
Stone, John H.   +7 more
openaire   +1 more source

Rituximab in ANCA-Associated Vasculitis

Current Rheumatology Reports, 2017
The purpose of this review is to describe the efficacy and safety of rituximab (RTX) as a remission induction and maintenance therapy in ANCA-associated vasculitis (AAV).A PubMed search was carried out to track down articles published between February 2006 and February 2016.
Romina I, Hassan, Angelo L, Gaffo
openaire   +2 more sources

Pathology of ANCA-associated vasculitis

Clinical and Experimental Nephrology, 2012
According to the recent 2012 Chapel Hill Consensus Conference, ANCA-associated vasculitis is classified in the group of small vessel vasculitis. Pauci-immune necrotizing crescentic glomerulonephritis is the morphological hallmark of ANCA-associated vasculitis.
Ferrario, F, Vanzati, A, PAGNI, FABIO
openaire   +2 more sources

ANCA-Associated Vasculitis

Advances in Kidney Disease and Health
ANCA-associated vasculitis (AAV) is a necrotizing, small-to-medium vessel vasculitis associated with significant morbidity and mortality. AAV is a systemic autoimmune disease affecting kidneys, eyes, sinuses, peripheral nerves, skin, and upper and lower respiratory tracts.
Purva Sharma, Reza Zonozi, Duvuru Geetha
openaire   +2 more sources

Management of ANCA associated vasculitis

BMJ, 2020
ABSTRACTAnti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a small to medium vessel vasculitis associated with excess morbidity and mortality. This review explores how management of AAV has evolved over the past two decades with pivotal randomized controlled trials shaping the management of induction and maintenance of remission.
Zachary S, Wallace, Eli M, Miloslavsky
openaire   +2 more sources

Pathogenesis of ANCA-Associated Vasculitis

Current Rheumatology Reports, 2012
Antineutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitides (AAV) are a group of systemic vasculitis syndromes characterized by inflammation and necrosis of blood vessel walls. Genetic, epigenetic, and environmental factors contribute to the etiology and pathogenesis of AAV.
Rodrigo, Cartin-Ceba   +2 more
openaire   +2 more sources

Novel Therapies for ANCA-associated Vasculitis

Current Rheumatology Reports, 2021
The purpose of this review is to discuss the most recent evidence on the treatment innovations and future prospective in the management of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs).In AAV, a growing body of research is available on novel treatment options for remission induction and to clarify some uncertainties ...
Monti S.   +5 more
openaire   +5 more sources

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