Results 131 to 140 of about 88,572 (244)
One Crisis to Solve Another? The Place of Care in a World of Automated Work
Journal of Social Philosophy, EarlyView.
Anca Gheaus
wiley +1 more source
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin +14 more
wiley +1 more source
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim +12 more
wiley +1 more source
PR3- and MPO-ANCA were determined by enzyme-linked immunosorbent assay (ELISA) and multiplex CytoBead microbead assay in 118 patients with ANCA-associated vasculitis, 300 with autoimmune and gastrointestinal diseases, 49 with infectious disorders, and ...
Rico Hiemann (355810) +13 more
core +1 more source
Tubulointerstitial Nephritis With Uveitis Syndrome: A Case Report and Review of Literature
ABSTRACT TINU syndrome should be considered in any child presenting with unexplained renal dysfunction and uveitis. Early recognition and a multidisciplinary approach involving nephrology and ophthalmology are essential to prevent irreversible renal and ocular damage.
Abdulelah Alshaiban
wiley +1 more source
Blocking C5L2 decreased C5a-primed neutrophils for ANCA-induced degranulation.
ANCA-induced neutrophil degranulation was determined by measuring the lactoferrin concentrations in the supernatant. Blocking C5L2 reduced ANCA-induced lactoferrin release.
Jun Yuan (356273) +4 more
core +1 more source
Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang +4 more
wiley +1 more source
MPO-C-ANCA-associated necrotising and crescentic glomerulonephritis
The patterns of ANCA staining usually relate closely to antibodies against myeloperoxidase and proteinase-3. C-ANCA is mainly antibodies to proteinase-3 and P-ANCA is antibodies to myeloperoxidase.
Abhilash Koratala +3 more
core +1 more source
Objective Positive antineutrophil cytoplasmic antibodies (ANCAs) may occur in the setting of interstitial lung disease (ILD), with or without ANCA‐associated vasculitis (AAV). We aim to compare the characteristics and clinical course of patients with ILD
Hao Cheng Shen +7 more
doaj +1 more source
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) is a rare, progressive cholangiopathy for which diagnosis remains challenging because of the absence of disease‐specific markers and the presence of secondary causes of sclerosing cholangitis (SSC) that closely mimic its clinical presentation. Diagnostic uncertainty can delay appropriate
Miki Scaravaglio +20 more
wiley +1 more source

