ABSTRACT Post‐translational modifications (PTMs) of proteins are essential to maintain homeostasis as many cellular processes rely on reversible PTMs. However, several PTMs, particularly irreversible PTMs in the extracellular space, can contribute to tissue dysfunction, inflammation, and may even trigger the development of autoimmunity against PTM ...
Marleen M. J. van Greevenbroek +1 more
wiley +1 more source
Cardiac Sympathetic Nerve Terminals in the Pathogenesis of Takotsubo Syndrome: A Brief Review and Novel Analytical Approach. [PDF]
Y-Hassan S.
europepmc +1 more source
Mapping the Altered Landscape of TCR Repertoire in Autoimmune Diseases
ABSTRACT Autoimmune diseases arise from the breakdown of immune tolerance through complex interactions between genetic predisposition, environmental exposures, and adaptive immune responses. High‐throughput T‐cell receptor (TCR) repertoire sequencing has transformed our ability to characterize these responses, providing unprecedented insights into ...
Celine Albalaa +3 more
wiley +1 more source
Mitral Valve Vegetation and Embolic Stroke in Newly Diagnosed Granulomatosis with Polyangiitis: A Diagnostic Challenge Mimicking Culture-Negative Endocarditis. [PDF]
Farhoud N, Farhoud H.
europepmc +1 more source
ABSTRACT Hypertension is a major determinant of chronic kidney disease progression, yet the relationship between standardized office blood pressure measurements (OBPM), chronic vascular lesions, and prognosis in biopsy‐proven glomerulonephritis (GN) remains poorly defined. We investigated the association between OBPM and renal histopathological lesions,
Antonietta Gigante +8 more
wiley +1 more source
From ANCA-mediated vascular injury to coronary microvascular and myocardial involvement in granulomatosis with polyangiitis: an immunocardiology perspective. [PDF]
Lucki M +4 more
europepmc +1 more source
Q-fever presenting as an autoimmune disease: case report and review
Gamaletsou Maria +2 more
doaj +1 more source
Microscopic polyangiitis with pulmonary involvement: Case Report. [PDF]
Ochoa-Andrade M +8 more
europepmc +1 more source
Tubulointerstitial Nephritis With Uveitis (TINU) Syndrome: A Case Series and Review of Literature
ABSTRACT Tubulointerstitial nephritis with uveitis (TINU) syndrome is a rare disorder characterised by the simultaneous or sequential occurrence of acute tubulointerstitial nephritis and uveitis, in the absence of systemic disease. Its true prevalence is likely underestimated, as renal and ocular manifestations may not appear concurrently. We conducted
Weaam Ali +5 more
wiley +1 more source
Clinical and Laboratory Transition Between GPA and EGPA. [PDF]
Fedosenko SV +8 more
europepmc +1 more source

