Results 201 to 210 of about 88,572 (244)

Clinical phenotypes of ANCA-associated vasculitis using ensemble clustering: prognostic and therapeutic insights from two Japanese cohorts. [PDF]

open access: yesRheumatology (Oxford)
Inoue H   +54 more
europepmc   +1 more source

ANCA-Associated Vasculitis [PDF]

open access: yesNature Reviews Disease Primers, 2020
Vasculitis is characterized by inflammation of the vascular wall. It reaches vessels of different sizes and locations, conditioning multisystem and complex manifestations that require a holistic approach. Antineutrophil cytoplasmic antibody-associated vasculitis has an annual incidence rate of 20 per million inhabitants.
Paul A Lyons   +2 more
exaly   +16 more sources

Pathophysiology of ANCA-Associated Vasculitides: Are ANCA Really Pathogenic? [PDF]

open access: yesKidney International, 2004
The strong relation between antineutrophil cytoplasmic autoantibodies (ANCA) and primary vasculitic syndromes suggests a pathophysiological role for ANCA. Experimental evidence for the pathogenic potential of ANCA has been derived from in vitro studies that demonstrate that ANCA can activate tumour necrosis factor alpha primed neutrophils, monocytes ...
Peter Heeringa, J W Cohen Tervaert
exaly   +6 more sources

Pathogenesis of PR3-ANCA Associated Vasculitis

open access: yesJournal of Autoimmunity, 2008
Wegener's Granulomatosis (WG) is closely associated with antineutrophil cytoplasmic autoantibodies (ANCA), particularly those directed to proteinase 3 (PR3).
C G M Kallenberg
exaly   +2 more sources

Immunopathogenesis of ANCA-Associated Vasculitis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune disorder which affects small- and, to a lesser degree, medium-sized vessels.
Kang Hyun Kim, Lee Smith, Keum Hwa Lee
exaly   +4 more sources

ANCA Vasculitis in the Elderly

JCR: Journal of Clinical Rheumatology, 2008
In population-based estimates of disease, the incidence of ANCA-associated vasculitides is increasing, with the peak age of onset in middle aged and older adults. Clinical characteristics of the very elderly have not been fully elucidated.Patients who met the criteria for Wegener granulomatosis and microscopic polyangiitis were included in the study ...
Deana D, Hoganson   +2 more
openaire   +2 more sources

Use of ANCA in diagnosis

Arthritis & Rheumatism, 2000
The study by John Stone and his colleagues, published in this issue of Arthritis Care and Research, is an important contribution to allow proper use and interpretation of anti-neutrophil cytoplasmic antibodies (ANCA) testing. The ANCA test is used to determine autoantibodies against proteinase-3 and myeloperoxidase, both antigens situated in the alpha ...
E C, Hagen, E A, van Gurp
openaire   +2 more sources

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