Results 51 to 60 of about 125,263 (264)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Control Effect Analysis and Engineering Application of Anchor Cable Beam-Truss Structure on Large-Deformation Roadway in Deep Coal Mine

open access: yesShock and Vibration
In response to the shortcomings of the small support scope of single anchor cable and failure to fully utilize the joint anchoring for surrounding rock, this study summarizes the classification of basic support forms for coal mine roadway surrounding ...
En Wang   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Research on mechanical property and engineering application of cable with high constant resistance and large deformation

open access: yes矿业科学学报, 2020
In recent years, the intensity and frequency of landslide geological disasters have been increasing year by year.In the process of landslide occurrence, the traditional prestressed anchor cable can not resist the large deformation of rock and cause ...
Tao Zhigang   +4 more
doaj   +1 more source

A Secure Localization Scheme for UASNs Based on Anchor Node Self-Adaptive Adjustment

open access: yesJournal of Marine Science and Engineering, 2023
The UASNs are widely used in underwater communications and monitoring, and many applications require accurate information regarding the position of nodes.
Ping Ding   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Investigation on Structural Performance of Integral Steel Wall Plate Structure in Cable–Pylon Anchorage Zone

open access: yesApplied Sciences
To enhance the bearing capacity of cable–pylon anchorage zones in cable-stayed bridges, this paper proposes the integral steel wall plate (IWP) structure and investigates the structural performance of its application in anchorage zones with a steel ...
Chen Liang   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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