Results 11 to 20 of about 271,635 (292)

How Does Diet Influence Our Lives? Evaluating the Relationship between Isotopic Signatures and Mortality Patterns in Italian Roman Imperial and Medieval Periods

Molecules, 2021
The present research investigates the relationship between dietary habits and mortality patterns in the Roman Imperial and Medieval periods. The reconstructions of population dynamics and subsistence strategies provide a fascinating source of information
Marica Baldoni, Alessandra Nardi, Flavio De Angelis, Olga Rickards, Cristina Martínez-Labarga   +4 more
doaj   +1 more source

A quantitative approach to detect and overcome PCR inhibition in ancient DNA extracts

BioTechniques, 2009
Inhibition is problematic in many applications of PCR, particularly those involving degraded or low amounts of template DNA, when simply diluting the extract is undesirable. Two basic approaches to monitoring inhibition in such samples using real-time or
Christine E. King, Régis Debruyne, Melanie Kuch, Carsten Schwarz, Hendrik N. Poinar   +4 more
doaj   +1 more source

Road blocks on paleogenomes - polymerase extension profiling reveals the frequency of blocking lesions in ancient DNA [PDF]

, 2010
Although the last few years have seen great progress in DNA sequence retrieval from fossil specimens, some of the characteristics of ancient DNA remain poorly understood. This is particularly true for blocking lesions, i.e.
Briggs, A., Heyn, P., Hofreiter, M., Kircher, M., Meyer, M., Stenzel, U.   +5 more
core   +2 more sources

Assessing the preservation of cytosine methylation in ancient DNA from five prehistoric Native American populations [PDF]

, 2015
textCytosine methylation of CpG dinucleotides is an important epigenetic mark that regulates gene expression in humans. While methylation patterns in extant populations have been widely studied, few studies have attempted to analyze methylation in ...
Smith, Ricky Wayne Aldon
core   +1 more source

Genetic characterisation of the North-West Indian populations: analysis of mitochondrial DNA control region variations

Annals of Human Biology, 2021
Background Human mitochondrial DNA presents several interesting characteristics, making it a favourable tool in the field of molecular anthropology, medical genetics, population history, and forensic science.
Gagandeep Singh, Srinivas Yellapu, Harkirat Singh Sandhu, Indu Sharma, Varun Sharma, A. J. S. Bhanwer   +5 more
doaj   +1 more source

Apolipoprotein E (APOE) Haplotypes in Healthy Subjects from Worldwide Macroareas: A Population Genetics Perspective for Cardiovascular Disease, Neurodegeneration, and Dementia

Current Issues in Molecular Biology, 2023
Human APOE is a 299-amino acid long protein expressed and secreted in several tissues and body districts, where it exerts different functions mainly related to lipid metabolism, with specific activities around cholesterol transport and absorption ...
Paolo Abondio, Francesco Bruno, Donata Luiselli   +2 more
doaj   +1 more source

Tuberculosis in Dr Granville's mummy: a molecular re-examination of the earliest known Egyptian mummy to be scientifically examined and given a medical diagnosis [PDF]

, 2010
‘Dr Granville's mummy’ was described to the Royal Society of London in 1825 and was the first ancient Egyptian mummy to be subjected to a scientific autopsy.
Abu Al-Soud W., Boom R., David E. Minnikin, Forbes B. A., Granville A. B., Gurdyal S. Besra, Harer W. B., Helen D. Donoghue, Hellyer T. J., John H. Taylor, Mark Spigelman, Minnikin D. E., Oona Y.-C. Lee, Tapp E., Taylor G. M., Taylor G. M.   +15 more
core   +2 more sources

Indigenous sex-selective salmon harvesting demonstrates pre-contact marine resource management in Burrard Inlet, British Columbia, Canada

Scientific Reports, 2021
To gain insight into pre-contact Coast Salish fishing practices, we used new palaeogenetic analytical techniques to assign sex identifications to salmonid bones from four archaeological sites in Burrard Inlet (Tsleil-Waut), British Columbia, Canada ...
Jesse Morin, Thomas C. A. Royle, Hua Zhang, Camilla Speller, Miguel Alcaide, Ryan Morin, Morgan Ritchie, Aubrey Cannon, Michael George, Michelle George, Dongya Yang   +10 more
doaj   +1 more source

A new home for microbes

eLife, 2019
Modern microorganisms growing in fossils provide major challenges for researchers trying to detect ancient molecules in the same fossils.
Raphael Eisenhofer, Alan Cooper
doaj   +1 more source

Genomic Approaches for Conservation Management in Australia under Climate Change

Life, 2021
Conservation genetics has informed threatened species management for several decades. With the advent of advanced DNA sequencing technologies in recent years, it is now possible to monitor and manage threatened populations with even greater precision ...
Isabelle R. Onley, Katherine E. Moseby, Jeremy J. Austin   +2 more
doaj   +1 more source