Results 111 to 120 of about 12,292,250 (327)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Expanding the Chemical Information Science gateway. [PDF]

F1000Res, 2021
Medina-Franco JL.
europepmc   +1 more source

Science, Government, and Information [PDF]

Science, 1963
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Impacts of covid-19 pandemic in the Brazilian research scenario on misinformation: Analysis of publications from information science journals. [PDF]

J Librariansh Inf Sci, 2022
de Assis SSD, Gerlin MNM.
europepmc   +1 more source

Information and communication media and Information Science

, 2014
Mídias como fenômenos contemporâneos de informação e comunicação são pouco exploradas no âmbito da Ciência da Informação (CI). O objetivo deste artigo é apresentar uma reflexão sobre o papel das mídias como ambientes de tramitação da informação que provocam mudanças no eco-sistema da criação de mensagens, de informação e de conhecimento socialmente ...
Jorente, Maria José Vicentini, Santos, Plácida L V A Costa   +1 more
openaire   +1 more source

Loop Calculus in Statistical Physics and Information Science

, 2006
Considering a discrete and finite statistical model of a general position we introduce an exact expression for the partition function in terms of a finite series.
A. Montanari, G. Parisi, J. Pearl, Michael Chertkov, R. G. Gallager, R. J. Baxter, Vladimir Y. Chernyak   +6 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

A scholarly network of AI research with an information science focus: Global North and Global South perspectives. [PDF]

PLoS One, 2022
Tang KY, Hsiao CH, Hwang GJ.
europepmc   +1 more source