Results 121 to 130 of about 12,292,250 (327)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
International Association of Aquatic and Marine Science Libraries and Information Centers
core +9 more sources
"OBE" Concept for New Training Mode of Electronic Information Science and Technology Professionals under Big Data Analysis. [PDF]
Liang J.
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
O presente trabalho tem como objetivo estudar o desenvolvimento e a institucionalização da Ciência da Informação no Brasil, analisando o grau de convergência entre a produção científica - materializada em teses e dissertações - e os marcos regulatórios ...
Regiane Alcântara Eliel
doaj
Forecasting the future of library and information science and its sub-fields. [PDF]
Taşkın Z.
europepmc +1 more source
Quantum Information Dynamics and Open World Science [PDF]
One of the fundamental insights of quantum mechanics is that complete knowledge of the state of a quantum system is not possible. Such incomplete knowledge of a physical system is the norm rather than the exception. This is becoming increasingly apparent
Bruza, Peter, Widdows, Dominic
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source

