Results 71 to 80 of about 9,614 (214)

Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen, Mathilde Rønne Koch, Cecilie Utke Rank, Christen Lykkegaard Andersen, Allan Weimann, Maria Thastrup, Tianwu Yang, Trine Meldgaard Lund, Ib Jarle Christensen, Flemming Nielsen, Tore Bjerregaard Stage, Sara Bisgaard Jensen, Mette Klarskov Andersen, Kjeld Schmiegelow, Kim Dalhoff   +14 more
wiley   +1 more source

Systemic menopausal hormone therapy treatment patterns in Danish women—A nationwide drug utilization study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Objectives This paper aims to describe the treatment patterns of contemporary systemic menopausal hormone therapy (MHT) in Denmark. Study design This study is a nationwide drug utilization study including an open cohort of all Danish women aged >40 years between 2000–2024.
Hannah K. Wood‐Kurland, Kathrine Kold Sørensen, Amalie Lykkemark Møller, Lina Steinrud Mørch, Mikkel Porsborg Andersen, Thomas Alexander Gerds, Amani Meaidi, Christian Torp‐Pedersen   +7 more
wiley   +1 more source

‘It is not a topic that should be assessed by a test’: Understanding teachers' assessment literacy in the teaching of ‘difficult histories’ such as the Holocaust

British Educational Research Journal, EarlyView.
Abstract This paper explores how history teachers in secondary education in England (a) see their role as assessors and (b) how they make decisions about assessing a difficult history: learning about the Holocaust. Assessment literacy (AL) is recognised as a potentially valuable aspect of good teaching and central to supporting students' learning ...
Mary Richardson, Rebecca Hale, Tom Haward, Kwaku Adjepong   +3 more
wiley   +1 more source

Lessons from primary school students' perceptions of the factors that influence school connectedness

British Educational Research Journal, EarlyView.
Abstract School connectedness is critical to improving students' health, development and wellbeing. Research into primary school students' perceptions of the factors that influence their sense of connectedness is essential for identifying practices that promote success.
Jordana F. Hoenig, Therese M. Cumming
wiley   +1 more source

Intern evaluering af undervisningen – fem år efter

Cepra-Striben, 2009
For fem år siden udgav Michael Andersen bogen Intern evaluering af undervisningen. I denne artikel reflekterer forfatteren over de forandringer, der siden da er sket i synet på, rammerne for og brugen af undervisningsevaluering. Michael Andersen arbejder
Michael Andersen
doaj   +1 more source

What drives animal responses to high severity fire? The role of functional traits

Biological Reviews, EarlyView.
ABSTRACT Fire regimes are changing worldwide, with increases in the frequency, extent, and severity of fires posing growing risks to biodiversity. Fire severity – the degree of habitat alteration following fire – strongly influences both immediate survival and long‐term recovery of fauna.
Grace A. Vielleux, Trent D. Penman, Victoria A. Reynolds, Matthew H. Swan   +3 more
wiley   +1 more source

A Business Framework for Product Take‐Back—A Structured Multiple‐Case Analysis

Business Strategy and the Environment, EarlyView.
ABSTRACT The potential of take‐back systems remains largely unrealized as initiatives have proven difficult to implement in practice. The question is why we do not see more take‐back systems given the substantial environmental benefits. We try to understand the challenges and stumbling blocks in setting up take‐back from a business perspective.
Rasmus Jørgensen, Torben Pedersen
wiley   +1 more source

The Impact of Sustainability Orientation and Sustainability Challenges in SME Responses to Institutional Support

Business Strategy and the Environment, EarlyView.
ABSTRACT SMEs receive increasing institutional support to embed sustainability, yet they vary widely in their ability to translate such support into practice. This study addresses this gap by examining the internal cognitive and strategic mechanism (sustainability orientation) through which managers interpret institutional support and the contextual ...
Michael Zisuh Ngoasong, Aqueel Imtiaz Wahga, Sam Zisuh Njinyah, Yen‐Jung Tseng   +3 more
wiley   +1 more source

Circular Economy in the Healthcare Industry: Developing a Circularity Assessment Tool for Complex Medical Devices

Business Strategy and the Environment, EarlyView.
ABSTRACT As the circular economy transition gains traction in the healthcare sector, extending the lifespan of complex medical devices has become a key priority, given their high cost and the challenges associated with their technological sophistication.
Tetiana Shevchenko, Lauren Durivault, Meisam Ranjbari, Zahra Shams Esfandabadi, Bernard Yannou, Robert Heidsieck, Michael Saidani, Ghada Bouillass   +7 more
wiley   +1 more source

Leveraging Reverse Engineering for CSCM Practices: Demystifying the Roles of Compositional Capability and Cooperative Orientation Under Humane Orientation and Competition Intensity

Business Strategy and the Environment, EarlyView.
ABSTRACT Circular supply chain management (CSCM) practices are seen as a solution for addressing society's many significant environmental challenges. Although existing studies recognise the importance of reverse engineering in combating poverty, there is limited knowledge about its effectiveness in shaping CSCM practices to address climate change and ...
Yaw Agyabeng‐Mensah, Charles Baah, Ebenezer Afum   +2 more
wiley   +1 more source