Results 151 to 160 of about 378,224 (340)
Sex differences in androgen sulphate formation in rats and mice [PDF]
David A. Lewis
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Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano+6 more
wiley +1 more source
THE EFFECT OF AGE, SEX, AND ANDROGEN ON BLOOD ERGOTHIONEINE
Julia B. Mackenzie, Cosmo G. Mackenzie
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The effect of nutrition and androgens on the composition of bovine blood plasma and seminal plasma at puberty [PDF]
Stamatis Baronos+3 more
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Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner+7 more
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EFFECT OF ANDROGENS ON PLASMA LEVELS OF 17-HYDROXYCORTICOSTEROIDS*
Carl Gemzell, G Notter
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Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert+3 more
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INTRACELLULAR REGULATIONS IN THE KIDNEY BY ANDROGENS [PDF]
Charles D. Kochakian
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What's New? While several nongenetic risk factors are linked to testicular germ‐cell tumors (TGCTs), the influence of environmental and hormonal factors remains unclear. This study evaluated the role of postnatal exposures in the etiology of TGCT using data from the ongoing EPSAM case–control investigation in Italy.
Mauro Cioffi+10 more
wiley +1 more source
The role of cytokines in ovarian cancer drug resistance
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang+7 more
wiley +1 more source