Inhibition of nuclear import suppresses androgen receptor action and overcomes resistance in prostate cancer. [PDF]
Wang X, Xu X, Fang S, Shi X, Yang Y.
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APUC-6 Genes as a Potential Prognostic and Predictive Biomarker in the CHAARTED Prostate Cancer Trial. [PDF]
Shi X +19 more
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Effects of Surgical and Medical Androgen Deprivation on Bladder Remodeling and Steroid Receptor Expression: An Experimental Rat Study. [PDF]
Yenmez MK, Sevinç C, Güler Y.
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Androgen Receptor Point Mutations: A Mechanism of Therapeutic Resistance and a Framework for Rational Drug Design. [PDF]
Colah A +6 more
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Abiraterone-Induced Hypokalemia and Hypophosphatemia: A Case Report. [PDF]
Safi A +10 more
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Precision Targeted Therapy for PCOS: Emerging Drugs, Translational Challenges, and Future Opportunities. [PDF]
Wu X, Yi W, Liu X.
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Intratumoral Androgens and Genetic Variants Driving Therapy Resistance in Prostate Cancer. [PDF]
Ye J +9 more
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Stress-related disorders and nonpeptidic CRH antagonists. [PDF]
Vlachakis D, Chrousos GP.
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Longitudinal [<sup>18</sup>F]FDG PET/MR Assessment of Arterial Inflammation in Patients With Prostate Cancer Undergoing Androgen Deprivation Therapy. [PDF]
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Recent Developments in Androgen Receptor Antagonists
Archiv Der Pharmazie, 2015The androgen receptor (AR), a ligand‐dependent transcription factor that regulates the expression of a series of downstream target genes after the binding of androgens, has been a target for the discovery of drugs used to treat prostate cancer. Prostate cancer always progresses to castration‐resistant prostate cancer after a period of androgen ...
Daoguang Zhang, Guisen Zhao
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