Results 161 to 170 of about 190,106 (204)
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Steroid derivatives as pure antagonists of the androgen receptor

The Journal of Steroid Biochemistry and Molecular Biology, 2012
While the androgens of testicular origin (representing about 50% of total androgens in men over 50 years) can be completely eliminated by surgical or medical castration with GnRH (gonadotropin-releasing hormone) agonists or antagonists, the antiandrogens currently available as blockers of androgen binding to the androgen receptor (AR), namely ...
Sylvain, Gauthier   +2 more
openaire   +2 more sources

Flutamide as an Androgen Antagonist on Epididymal Function in the Rat*

Andrologia, 2009
The purpose of this study was to investigate whether flutamide (alpha-alpha-alpha--Trifluro-2-methyl-4'-nitro-m-propionatoluidide), a nonsteroidal compound acts as an androgen antagonist at the level of the epididymis. For comparison, cyproterone acetate was also evaluated under identical experimental conditions. The levels of glycerylphosphorylcholine
J D, Dhar, S R, Srivastava, B S, Setty
openaire   +2 more sources

Assays to Measure Estrogen and Androgen Agonists and Antagonists

1998
Substantial evidence has surfaced on the hormone-like effects of many xenobiotics in fish, wildlife and humans (Colborn et al., 1993). The endocrine and reproductive effects of xenobiotics are believed to be due to their 1) mimicking the effects of endogenous hormones such as estrogens and androgens, 2) antagonizing the effects of normal, endogenous ...
A M, Soto   +6 more
openaire   +2 more sources

Androgen antagonists

Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology, 1975
openaire   +2 more sources

Androgen Biosynthesis Inhibitors and Androgen Receptor Antagonists

2004
Stephen E. Borst   +2 more
openaire   +1 more source

Synthesis and SAR of potent and selective androgen receptor antagonists: 5,6-Dichloro-benzimidazole derivatives

Bioorganic and Medicinal Chemistry Letters, 2007
Olivia Linton   +2 more
exaly  

Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists

Bioorganic and Medicinal Chemistry Letters, 2005
Aaron Balog, Weifang Shan, Kevin Kish
exaly  

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